C₂₅H₁₉NO₂

Base Information

• Chemical Name: C₂₅H₁₉NO₂
• CAS No.: 1449795-44-1
• Molecular Formula: C₂₅H₁₉NO₂
• Molecular Weight: 365.431
• Mol file: 1449795-44-1.mol

Synonyms:C₂₅H₁₉NO₂

Chemical Property of C₂₅H₁₉NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₅H₁₉NO₂

There total 4 articles about C₂₅H₁₉NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C11H11NO2 (1449795-77-0) + diphenyl acetylene (501-65-5) → C25H19NO2 (1449795-44-1)

Guidance literature:

With oxygen; copper diacetate; palladium diacetate; In dimethyl sulfoxide; at 20 ℃; for 72h;

DOI:10.1002/adsc.201300512

Reference yield: 99.0%

→ C25H19NO2 (1449795-44-1)

Guidance literature:

With oxygen; copper diacetate; palladium diacetate; In dimethyl sulfoxide; at 20 ℃; for 72h; under 760.051 Torr;

Reference yield:

3-ethyl-6-hydroxyacetophenone (24539-92-2) → C25H19NO2 (1449795-44-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / toluene / 110 °C

2: ammonium acetate / toluene / 130 °C

3: palladium diacetate; copper diacetate; oxygen / dimethyl sulfoxide / 72 h / 20 °C

With ammonium acetate; oxygen; copper diacetate; palladium diacetate; sodium hydride; In dimethyl sulfoxide; toluene;

DOI:10.1002/adsc.201300512

upstream raw materials:

3-ethyl-6-hydroxyacetophenone

6-ethyl-4-hydroxycoumarin

C₁₁H₁₁NO₂

diphenyl acetylene

Refernces

• 1、 Peng, Shiyong,Wang, Lei,Huang, Jiayao,Sun, Shaofa,Guo, Haibing,Wang, Jian. "Palladium-catalyzed oxidative annulation via C-H/N-H functionalization: Access to substituted pyrroles". . p. 2550 - 2557. Retrieved 2013/10/21.