Desonide

Base Information Edit

Chemical Name:Desonide
CAS No.:638-94-8
Molecular Formula:C24H32O6
Molecular Weight:416.514
Hs Code.:2937290000
European Community (EC) Number:211-351-6
UNII:J280872D1O
DSSTox Substance ID:DTXSID7046756
Nikkaji Number:J6.927B
Wikipedia:Desonide
Wikidata:Q904011
NCI Thesaurus Code:C61702
RXCUI:3254
Pharos Ligand ID:533YDP4RC7AW
Metabolomics Workbench ID:43466
ChEMBL ID:CHEMBL1201109
Mol file:638-94-8.mol

Synonyms:Desocort;Desone;Desonide;Desowen;Locapred;Locatop;Prednacinolone;Tridésonit;Tridesilon

Suppliers and Price of Desonide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Desonide
100mg
$ 215.00

TCI Chemical
Desonide
250MG
$ 27.00

TCI Chemical
Desonide
1G
$ 74.00

TCI Chemical
Desonide
5G
$ 254.00

DC Chemicals
Desonide >99%
250 mg
$ 500.00

DC Chemicals
Desonide >99%
1 g
$ 1000.00

Chemtos
Desonide-Labeled13C3
25 mg
$ 1310.00

ChemScene
Desonide 99.45%
100mg
$ 120.00

ChemScene
Desonide 99.45%
10mg
$ 96.00

ChemScene
Desonide 99.45%
500mg
$ 360.00

Total 197 raw suppliers

Chemical Property of Desonide Edit

Chemical Property:

Appearance/Colour:Powder
Vapor Pressure:7.16E-16mmHg at 25°C
Melting Point:274 - 275oC
Refractive Index:1.598
Boiling Point:580.1 °C at 760 mmHg
PKA:12.87±0.10(Predicted)
Flash Point:196.9 °C
PSA：93.06000
Density:1.3 g/cm³
LogP:2.32670
Storage Temp.:Refrigerator
Solubility.:DMF (Slightly, Sonicated), DMSO (Sparingly), Methanol (Slightly, Heated)
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:416.21988874
Heavy Atom Count:30
Complexity:873

Purity/Quality:

98.0%-102.0% ^*data from raw suppliers

Desonide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C)C
Isomeric SMILES:C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)CCC5=CC(=O)C=C[C@]35C)O
Recent ClinicalTrials:Proton Pump Inhibitors Use in Patients With Psoriasis
Recent EU Clinical Trials:An intra-individual randomized controlled study to evaluate the efficacy and tolerance of the product RV4421A BS0042 in association with a moderately potent topical corticosteroid in adults with Atopic Dermatitis
Uses antifungal Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490). Desonide(Budesonide EP Impurity F) is an impurity of Budesonide (B689490), an anti-inflammatory.
Indications Desonide (DesOwen, Tridesilon) is a synthetic corticosteroid.
Therapeutic Function Antiinflammatory

Technology Process of Desonide

There total 11 articles about Desonide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%