Technology Process of benzyl (3-(4-methoxylphenyl)-2-propynyl)oxycarbamate
There total 4 articles about benzyl (3-(4-methoxylphenyl)-2-propynyl)oxycarbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
O-(3-(4-methoxyphenyl)-2-propynyl)hydroxylamine;
With
sodium hydrogencarbonate;
In
1,4-dioxane; water;
at 20 ℃;
for 0.5h;
benzyl chloroformate;
In
1,4-dioxane; water;
for 1h;
DOI:10.1021/jo200407b
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: carbon tetrabromide / dichloromethane / 0.17 h / 0 °C
1.2: 0 - 20 °C
2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 20 °C
3.1: hydrazine hydrate / methanol; dichloromethane / 20 °C
4.1: sodium hydrogencarbonate / 1,4-dioxane; water / 0.5 h / 20 °C
4.2: 1 h
With
carbon tetrabromide; sodium hydrogencarbonate; hydrazine hydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo200407b
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 20 °C
2.1: hydrazine hydrate / methanol; dichloromethane / 20 °C
3.1: sodium hydrogencarbonate / 1,4-dioxane; water / 0.5 h / 20 °C
3.2: 1 h
With
sodium hydrogencarbonate; hydrazine hydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo200407b
