C₁₄H₁₃Cl₂NO₂

Base Information

• Chemical Name: C₁₄H₁₃Cl₂NO₂
• CAS No.: 1440062-60-1
• Molecular Formula: C₁₄H₁₃Cl₂NO₂
• Molecular Weight: 298.169
• Mol file: 1440062-60-1.mol

Synonyms:C₁₄H₁₃Cl₂NO₂

Chemical Property of C₁₄H₁₃Cl₂NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₃Cl₂NO₂

There total 3 articles about C₁₄H₁₃Cl₂NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4'-Dichlorobiphenyl ether (6842-62-2) → C14H13Cl2NO2 (1440062-60-1)

Guidance literature:

Multi-step reaction with 3 steps

1: aluminum (III) chloride / dichloromethane / 2 h / 5 - 20 °C / Inert atmosphere

2: hydroxylamine hydrochloride / ethanol / 5 h / Reflux; Inert atmosphere

3: sodium tetrahydroborate; iodine / tetrahydrofuran / 7.5 h / 0 °C / Reflux; Inert atmosphere

With aluminum (III) chloride; sodium tetrahydroborate; hydroxylamine hydrochloride; iodine; In tetrahydrofuran; ethanol; dichloromethane; 1: |Friedel-Crafts Acylation;

DOI:10.1039/c3nj00032j

Reference yield:

C16H13Cl2NO4 (1440061-93-7) → C14H13Cl2NO2 (1440062-60-1)

Guidance literature:

With sodium tetrahydroborate; iodine; In tetrahydrofuran; at 0 ℃; for 7.5h; Reflux; Inert atmosphere;

DOI:10.1039/c3nj00032j

Reference yield:

C16H12Cl2O4 (1440061-23-3) → C14H13Cl2NO2 (1440062-60-1)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride / ethanol / 5 h / Reflux; Inert atmosphere

2: sodium tetrahydroborate; iodine / tetrahydrofuran / 7.5 h / 0 °C / Reflux; Inert atmosphere

With sodium tetrahydroborate; hydroxylamine hydrochloride; iodine; In tetrahydrofuran; ethanol;

DOI:10.1039/c3nj00032j

upstream raw materials:

C₁₆H₁₃Cl₂NO₄

C₁₆H₁₂Cl₂O₄

3,4'-Dichlorobiphenyl ether

Downstream raw materials:

C₂₁H₁₅Cl₂F₂NO₃

4-(2-chloro-4-(4-chlorophenoxy)phenyl)-2-(2,6-difluorophenyl)-1,3-oxazoline

C₂₁H₁₄Cl₃F₂NO₂

Refernces