Tetrahydro-3,6-pyridazinedione

Base Information

• Chemical Name: Tetrahydro-3,6-pyridazinedione
• CAS No.: 502-95-4
• Molecular Formula: C4H6N2O2
• Molecular Weight: 114.104
• Hs Code.: 2933990090
• European Community (EC) Number: 684-380-9
• NSC Number: 15048
• UNII: 0NTK7OE1HR
• DSSTox Substance ID: DTXSID30198242
• Wikidata: Q83071017
• Mol file: 502-95-4.mol

Synonyms:Tetrahydro-3,6-pyridazinedione;502-95-4;Succinic hydrazide;diazinane-3,6-dione;Hexahydro-3,6-pyridazinedione;Succinic acid, cyclic hydrazide;3,6-Pyridazinedione, tetrahydro-;Butanedioic acid, cyclic hydrazide;Tetrahydro-3, 6-pyridazinedione;0NTK7OE1HR;tetrahydropyridazine-3,6-dione;1,2-DIAZINANE-3,6-DIONE;NSC-15048;3, tetrahydro-;NSC 15048;UNII-0NTK7OE1HR;3,6-Pyridazinedione, tetrahydro- (8CI)(9CI);CYCLIC SUCCINHYDRAZIDE;SCHEMBL906641;Tetrahydro-pyridazin-3,6-dion;DTXSID30198242;RNCAJLLRSYSZAM-UHFFFAOYSA-N;NSC15048;AKOS024428846;3,6(1H,2H)-Pyridazinedione, dihydro-;FT-0742868;D87745

Chemical Property of Tetrahydro-3,6-pyridazinedione

Chemical Property:

• Vapor Pressure: 4.8E-08mmHg at 25°C
• Melting Point: 277-278 °C(Solv: ethanol (64-17-5))
• Boiling Point: 443°C at 760 mmHg
• PKA: 11.08±0.20(Predicted)
• Flash Point: 238.2°C
• PSA: 58.20000
• Density: 1.246g/cm³
• LogP: -0.41480
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 114.042927438
• Heavy Atom Count: 8
• Complexity: 116

Purity/Quality:

98%min ^*data from raw suppliers

TETRAHYDRO-3,6-PYRIDAZINEDIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(=O)NNC1=O

Technology Process of Tetrahydro-3,6-pyridazinedione

There total 6 articles about Tetrahydro-3,6-pyridazinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Maleic hydrazide (123-33-1) → tetrahydropyridazine-3,6-dione (502-95-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1021/jo049396d

Reference yield:

succinic acid anhydride (108-30-5) → tetrahydropyridazine-3,6-dione (502-95-4)

Guidance literature:

With hydrazine hydrate; at 25 ℃; for 0.0833333h;

DOI:10.1016/j.tetlet.2016.01.074

Reference yield:

C15H12F17NO3 → tetrahydropyridazine-3,6-dione (502-95-4)

Guidance literature:

With hydrazine; at 20 ℃;

DOI:10.1021/ol702915e

upstream raw materials:

Maleic hydrazide

3,6-dihydroxypyridazine

succinic acid anhydride

hydrazine hydrate

Downstream raw materials:

1,2-Diacetyl-perhydropyridazindion-3,6

Perhydro-1,4,6,9-tetraketo-pyridazo<1,2-a>pyridazin

1,2-dimethyltetrahydropyridazine-3,6-dione

3,6-dibromopyridazine

Refernces

• 1、 Hinman,Landborg. "-". . p. 724. Retrieved 1959.
• 2、 Stoessl. "-". . p. 2430. Retrieved 1965.
• 3、 Rafeeq,Srinivasa Reddy,Venkata Ramana Reddy,Naidu,Dubey. "Green and efficient synthesis of 2-(4-oxo-3,4-dihydroquinazolin-2-yl)-2,3-dihydropthalazine-1,4-dione". . p. 412 - 417. Retrieved 2015/03/31.