2-Octadecanone

Base Information

• Chemical Name: 2-Octadecanone
• CAS No.: 7373-13-9
• Molecular Formula: C18H36O
• Molecular Weight: 268.483
• Mol file: 7373-13-9.mol

Synonyms:Hexadecyl methyl ketone;

Chemical Property of 2-Octadecanone

Chemical Property:

• Vapor Pressure: 0.000287mmHg at 25°C
• Melting Point: 50-54℃
• Refractive Index: 1.442
• Boiling Point: 332.1 °C at 760 mmHg
• Flash Point: 77.6 °C
• PSA: 17.07000
• Density: 0.831 g/cm³
• LogP: 6.44680

Purity/Quality:

99%, ^*data from raw suppliers

2-OCTADECANONE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Octadecanone

There total 24 articles about 2-Octadecanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-nitro-2-(pyridine-2-thiyl)octadecane (104543-12-6) → octadecan-2-one (7373-13-9)

Guidance literature:

With titanium(III) chloride; In tetrahydrofuran; water; Ambient temperature;

DOI:10.1016/S0040-4020(01)91351-1

Reference yield: 59.0%

octadec-1-ene (112-88-9) → octadecan-2-one (7373-13-9) + octadecan-2-ol (593-32-8)

Guidance literature:

With tris(dibenzoylmethano)iron(III); phenylsilane; In ethanol; at 20 ℃; for 7h; Reagent/catalyst;

DOI:10.1002/anie.202103222

Reference yield: 38.0%

Phenethyl-prop-(E)-ylidene-amine (392686-83-8) + (2Z,4E)-3-hydroxy-6-oxodocosa-2,4-dienoic acid methyl ester (852152-06-8) → octadecan-2-one (7373-13-9) + (2R,3R,4R)-2-Ethyl-4-hydroxy-5-[2-oxo-octadec-(E)-ylidene]-1-phenethyl-pyrrolidine-3-carboxylic acid methyl ester + (2S,3S,4R)-2-Ethyl-4-hydroxy-5-[2-oxo-octadec-(E)-ylidene]-1-phenethyl-pyrrolidine-3-carboxylic acid methyl ester

Guidance literature:

In chloroform-d1; at 20 ℃; for 288h;

DOI:10.1016/j.tetlet.2005.02.124

upstream raw materials:

(S)-octadecan-2-ol

pentadecyl bromide

sodium ethyl acetylacetate enolate

heptadecanoic acid

Downstream raw materials:

octadecan-2-one oxime

3-methyl-nonadec-1-yn-3-ol

octadecan-2-ol

octadecan-2-one semicarbazone

Refernces

• 1、 Zhao, Tingting,Li, Fuwei,Yu, Hongchang,Ding, Shilei,Li, Zhixia,Huang, Xinyuan,Li, Xiang,Wei, Xiaohan,Wang, Zhenlin,Lin, Hongfei. "Synthesis of mesoporous ZSM-5 zeolites and catalytic cracking of ethanol and oleic acid into light olefins". . p. 101 - 110. Retrieved 2019/02/24.
• 2、 Escola,Botas,Vargas,Bravo. "Oxidation of heavy 1-olefins (C12= s(-) C20=) with TBHP using a modified Wacker system". experimental part. p. 34 - 39. Retrieved 2010/06/12.