9H-fluorene-4-carbonyl chloride

Base Information

• Chemical Name: 9H-fluorene-4-carbonyl chloride
• CAS No.: 7315-93-7
• Molecular Formula: C₁₄H₉ClO
• Molecular Weight: 228.678
• Hs Code.: 2916399090
• NSC Number: 171606
• DSSTox Substance ID: DTXSID70305756
• Wikidata: Q82052487
• Mol file: 7315-93-7.mol

Synonyms:9H-fluorene-4-carbonyl chloride;7315-93-7;NSC171606;SCHEMBL10615338;DTXSID70305756;MFCD11520754;AKOS005173594;NSC-171606;LS-03826

Chemical Property of 9H-fluorene-4-carbonyl chloride

Chemical Property:

• Vapor Pressure: 6.27E-06mmHg at 25°C
• Melting Point: 76 °C
• Boiling Point: 378.5°Cat760mmHg
• Flash Point: 182.3°C
• PSA: 17.07000
• Density: 1.308g/cm³
• LogP: 3.63680
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 228.0341926
• Heavy Atom Count: 16
• Complexity: 289

Purity/Quality:

98%min ^*data from raw suppliers

9H-Fluorene-4-carbonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2=C(C3=CC=CC=C31)C(=CC=C2)C(=O)Cl

Technology Process of 9H-fluorene-4-carbonyl chloride

There total 2 articles about 9H-fluorene-4-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fluorene-4-carboxylic acid (6954-55-8) → fluorene-4-carboxylic acid chloride (7315-93-7)

Guidance literature:

With thionyl chloride;

DOI:10.1021/jo01161a010

Reference yield:

→ fluorene-4-carboxylic acid chloride (7315-93-7)

Guidance literature:

Fluoren-carbonsaeure-(4), SOCl2, sd. Bzl.;

Reference yield:

fluorene-4-carboxylic acid chloride (7315-93-7) → 9-(5-phenyl-1,2-dithiol-3-ylidene)-2,5,7-trinitro-4-[(3,6,9-trioxadecyl)oxycarbonyl]fluorene

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / DMF / 15 h / 80 - 85 °C

2: 51 percent / fuming HNO₃; conc. H₂SO₄ / -8 - 20 °C

3: 65 percent / dimethylformamide / 20 h / 20 °C

With sulfuric acid; nitric acid; N,N-dimethyl-formamide; In N,N-dimethyl-formamide; 1: Esterification / 2: Nitration / 3: Substitution;

DOI:10.1021/jo990100r

upstream raw materials:

fluorene-4-carboxylic acid

Downstream raw materials:

fluorene-4-carbanilide

biphenyl-2-yl-fluoren-4-yl ketone

fluorene-4-carbothioic acid S-phenyl ester

fluorene-4-carboxamide

Refernces

• 1、 -. "Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof". Page/Page column 25. . Retrieved 2008/12/06.
• 2、 Skabara, Peter J.,Serebryakov, Igor M.,Perepichka, Igor F.. "Electron acceptors of the fluorene series. Part 8. Electrochemical and intramolecular charge transfer studies of thiophene functionalised fluorenes". . p. 505 - 513. Retrieved 2007/10/03.