2-Amino-N,3-dihydroxypropanamide

Base Information

• Chemical Name: 2-Amino-N,3-dihydroxypropanamide
• CAS No.: 55779-32-3
• Molecular Formula: C₃H₈N₂O₃
• Molecular Weight: 120.108
• NSC Number: 517349
• DSSTox Substance ID: DTXSID301301599
• Nikkaji Number: J1.785.991I
• Wikidata: Q27145350
• ChEMBL ID: CHEMBL568191
• Mol file: 55779-32-3.mol

Synonyms:serine hydroxamate;serine hydroxamate, (+-)-isomer

Chemical Property of 2-Amino-N,3-dihydroxypropanamide

Chemical Property:

• PSA: 99.07000
• LogP: -0.64800
• Storage Temp.: −20°C
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 120.05349212
• Heavy Atom Count: 8
• Complexity: 84.6

Purity/Quality:

98%,99%, ^*data from raw suppliers

DL-Serine hydroxamate seryl-tRNA synthetase inhibitor ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)NO)N)O
• Uses: Serine has been used as an inhibitor of seryl-tRNA synthetase. DL-Serine hydroxamate is used to induce metabolic synthesis of guanosine 3′-diphosphate 5′-diphosphate (ppGpp) in E. coli by amino acid starvation. It is also used to synchronize cell cycle in E. coli cultures by inhibition of tRNA charging.

Technology Process of 2-Amino-N,3-dihydroxypropanamide

There total 1 articles about 2-Amino-N,3-dihydroxypropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Ser-OMe (2104-89-4,2788-84-3,24184-43-8) → serine hydroxamate (55779-32-3)

Guidance literature:

With hydroxylamine; In methanol;

upstream raw materials:

Ser-OMe

Refernces