(2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether

Base Information

• Chemical Name: (2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether
• CAS No.: 515813-57-7
• Molecular Formula: C₂₃H₂₄O₇
• Molecular Weight: 412.439
• Mol file: 515813-57-7.mol

Synonyms:(2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether

Chemical Property of (2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether

There total 5 articles about (2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(2-amino-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether (515813-56-6) → (2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether (515813-57-7)

Guidance literature:

(2-amino-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether; With sulfuric acid; sodium nitrite; In water; at 5 ℃; for 1h;

With sulfuric acid; sodium sulfate; In water; for 0.0833333h; Heating;

DOI:10.1016/S0957-4166(02)00742-5

Reference yield:

4-fluoro-3-nitrobenzaldehyde (42564-51-2) → (2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether (515813-57-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 91 percent / potassium carbonate; tetra-n-butylammonium chloride / 0.08 h / microwave irradiation

2.1: 81 percent / pyridine; piperidine / 6 h / 120 °C

3.1: 92 percent / iron; iron(II) sulfate / H₂O / 3 h / Heating

4.1: sodium nitrite; sulfuric acid / H₂O / 1 h / 5 °C

4.2: 84 percent / sulfuric acid; sodium sulfate / H₂O / 0.08 h / Heating

With piperidine; pyridine; sulfuric acid; tetrabutyl-ammonium chloride; iron; potassium carbonate; iron(II) sulfate; sodium nitrite; In water;

DOI:10.1016/S0957-4166(02)00742-5

Reference yield:

4-(4-formyl-2-methoxyphenoxy)-3-nitrobenzaldehyde (92498-33-4) → (2-hydroxy-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether (515813-57-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 81 percent / pyridine; piperidine / 6 h / 120 °C

2.1: 92 percent / iron; iron(II) sulfate / H₂O / 3 h / Heating

3.1: sodium nitrite; sulfuric acid / H₂O / 1 h / 5 °C

3.2: 84 percent / sulfuric acid; sodium sulfate / H₂O / 0.08 h / Heating

With piperidine; pyridine; sulfuric acid; iron; iron(II) sulfate; sodium nitrite; In water;

DOI:10.1016/S0957-4166(02)00742-5

upstream raw materials:

(2-amino-2'-methoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether

4-(4-formyl-2-methoxyphenoxy)-3-nitrobenzaldehyde

4-fluoro-3-nitrobenzaldehyde

vanillin

Downstream raw materials:

(2,2'-dimethoxy-4,4'-di(3-hydroxy-1-propenyl))diphenyl ether

(2,2'-dimethoxy-4,4'-di(2-ethoxycarbonylethenyl))diphenyl ether

Refernces