tri-p-tolyl-acetic acid

Base Information

• Chemical Name: tri-p-tolyl-acetic acid
• CAS No.: 860539-65-7
• Molecular Formula: C₂₃H₂₂O₂
• Molecular Weight: 330.426
• Mol file: 860539-65-7.mol

Synonyms:tri-p-tolyl-acetic acid

Chemical Property of tri-p-tolyl-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tri-p-tolyl-acetic acid

There total 8 articles about tri-p-tolyl-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tri-p-tolylmethane (16845-02-6) → tri-p-tolyl-acetic acid (860539-65-7)

Guidance literature:

With diethyl ether; cumyl potassium; anschliessendes Einleiten von Kohlendioxid;

DOI:10.1021/ja01260a027

Reference yield:

tri-p-tolylmethylchloride (971-93-7) → tri-p-tolyl-acetic acid (860539-65-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous formic acid

2: 1-methyl-1-phenyl-ethyl potassium; diethyl ether / anschliessendes Einleiten von Kohlendioxid

With formic acid; diethyl ether; cumyl potassium;

DOI:10.1021/ja01260a027

Reference yield:

para-methylphenylmagnesium bromide (4294-57-9) → tri-p-tolyl-acetic acid (860539-65-7)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.83 h / Heating

2: Na₂CO₃ / 2 h / Heating

With sodium carbonate; In tetrahydrofuran;

DOI:10.1002/(SICI)1099-1395(199707)10:7<499::AID-POC896>3.0.CO;2-2

upstream raw materials:

tri-p-tolylmethane

bis-p-tolylhydroxyacetic acid

toluene

formic acid

Downstream raw materials:

tris(4-methylphenyl)methanol

tri-p-tolylmethane

Refernces