3-Bromopropylazanium;bromide

Base Information

• Chemical Name: 3-Bromopropylazanium;bromide
• CAS No.: 5003-71-4
• Molecular Formula: C3H8BrN^.HBr
• Molecular Weight: 218.919
• Hs Code.: 29211980
• Mol file: 5003-71-4.mol

Synonyms:3-bromopropylazanium;bromide;bromopropylammonium bromide

Chemical Property of 3-Bromopropylazanium;bromide

Chemical Property:

• Appearance/Colour: white to off-white powder or chunks
• Vapor Pressure: 3.81mmHg at 25°C
• Melting Point: 171-172 °C(lit.)
• Boiling Point: 150.6 °C at 760 mmHg
• Flash Point: 44.9 °C
• PSA: 26.02000
• LogP: 2.38850
• Storage Temp.: Store at R.T.
• Sensitive.: Hygroscopic
• Water Solubility.: Soluble in water (50 mg/ml).
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 218.90813
• Heavy Atom Count: 6
• Complexity: 16.4

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

3-Bromopropylamine hydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C[NH3+])CBr.[Br-]
• Uses: 3-Bromopropylamine hydrobromide is used as pharmaceutical raw materials and intermediates. Homotaurine is synthesized from 3-bromopropylamine hydrobromide. 3-Bromopropylamine hydrobromide is commonly used as a reagent to introduce propylamine group to the molecular skeleton. Some of the other reported applications include:Synthesis of photochemically and thermally reactive azobenzene rotaxane and indolocarbazole-containing [2]rotaxane.Synthesis of indenoisoquinoline based active topoisomerase I inhibitors as anticancer agents.

Technology Process of 3-Bromopropylazanium;bromide

There total 3 articles about 3-Bromopropylazanium;bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 3-bromopropylamine hydrochloride (5003-71-4)

Guidance literature:

Reference yield: 55.0%

propan-1-ol-3-amine (156-87-6) → 3-bromopropylamine hydrochloride (5003-71-4)

Guidance literature:

With hydrogen bromide; In water; Reflux;

DOI:10.1111/cbdd.12092

Reference yield:

→ 3-bromopropylamine hydrochloride (5003-71-4)

Guidance literature:

With hydrogen bromide; at 180 - 220 ℃;

upstream raw materials:

propan-1-ol-3-amine

Downstream raw materials:

S-aminopropylisothiourea

1-(3-bromopropyl)-1H-pyrrole

4-Benzyloxycarbonylamino-N-(3-bromopropyl)butanamide

2-(3-Amino-propylsulfanyl)-6-bromo-3-(2-methoxy-phenyl)-3H-quinazolin-4-one

Refernces

• 1、 -. "TEMPLATES FOR NUCLEATION AND PROPAGATION OF PEPTIDE SECONDARY STRUCTURE". . . Retrieved 2010/09/17.