4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole

Base Information

• Chemical Name: 4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole
• CAS No.: 74294-62-5
• Molecular Formula: C₁₂H₁₃N₅O₂S
• Molecular Weight: 291.334
• Mol file: 74294-62-5.mol

Synonyms:4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole

Chemical Property of 4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole

There total 3 articles about 4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

NO-bis-p-tolylsulphonylhistaminol (74294-60-3) → 4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole (74294-62-5)

Guidance literature:

With lithium azide; In N,N-dimethyl-formamide; at 21 ℃; for 18h;

Reference yield:

2-(1H-imidazol-4-yl)ethanol (872-82-2) → 4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole (74294-62-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 336 mg / pyridine / 2 h / -23 °C

2: 180 mg / lithium azide / dimethylformamide / 18 h / 21 °C

With pyridine; lithium azide; In N,N-dimethyl-formamide;

Reference yield:

histamine hydrochloride (55-36-7) → 4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole (74294-62-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 34 mg / ethanol, NAD+, liver alcohol dehydrogenase, catalase, diamine oxidase from pea seedling / 48 h / 37 °C / phosphate buffer (pH 7)

2: 336 mg / pyridine / 2 h / -23 °C

3: 180 mg / lithium azide / dimethylformamide / 18 h / 21 °C

With pyridine; lithium azide; ethanol; diamine oxidase from pea seedling; liver alcohol dehydrogenase; NAD; catalase; In N,N-dimethyl-formamide;

upstream raw materials:

NO-bis-p-tolylsulphonylhistaminol

2-(1H-imidazol-4-yl)ethanol

histamine hydrochloride

Downstream raw materials:

histamine dichloride

Refernces