2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate

Base Information

• Chemical Name: 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate
• CAS No.: 165190-72-7
• Molecular Formula: CF₃O₃S*C₁₂H₁₄NOS
• Molecular Weight: 369.386
• Mol file: 165190-72-7.mol

Synonyms:2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate

Chemical Property of 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate

There total 1 articles about 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.4%

2-(α-hydroxybenzyl)-4-methylthiazole (54918-64-8) + methyl trifluoromethanesulfonate (333-27-7) → 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate (165190-72-7)

Guidance literature:

In diethyl ether; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2008.06.008

Reference yield: 46.0%

4-bromonitrosobenzene (3623-23-2) + 4-nitro-benzoyl chloride (122-04-3) + 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate (165190-72-7) → O-benzoyl-N-(4-nitrobenzoyl)-N-(4-bromophenyl)hydroxylamine (82461-71-0) + 1,2-bis(4-bromophenyl)diazene oxide (1215-42-5,21650-67-9,125367-64-8)

Guidance literature:

4-bromonitrosobenzene; 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate; In dichloromethane; at 20 ℃;

4-nitro-benzoyl chloride; With sodium hydride; In tetrahydrofuran; at -30 - 20 ℃; Further stages.;

DOI:10.1016/j.tet.2008.06.008

Reference yield: 46.0%

4-nitrosonitrobenzene (4485-08-9) + acetyl chloride (75-36-5) + 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate (165190-72-7) → C15H12N2O5 (1047663-42-2) + bis(4-nitrophenyl)diazene (3646-57-9,89103-79-7) + 4,4'-dinitroazoxybenzene (614-25-5,21650-71-5,71297-95-5)

Guidance literature:

4-nitrosonitrobenzene; 2-(α-hydroxybenzyl)-3,4-dimethylthiazolium trifluoromethanesulfonate; In dichloromethane; at 20 ℃;

acetyl chloride; With sodium hydride; In tetrahydrofuran; at -30 - 20 ℃; Further stages.;

DOI:10.1016/j.tet.2008.06.008

upstream raw materials:

2-(α-hydroxybenzyl)-4-methylthiazole

methyl trifluoromethanesulfonate

Downstream raw materials:

3,3'-dimethylazoxybenzene

N-(3-methylphenyl)benzohydroxamic acid

4,4'-bis(chloro)azoxybenzene

N-(4-chlorophenyl)benzohydroxamic acid

Refernces