Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester

Base Information

• Chemical Name: Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester
• CAS No.: 96824-29-2
• Molecular Formula: C₂₀H₂₇N₂O₄P
• Molecular Weight: 390.419
• Mol file: 96824-29-2.mol

Synonyms:Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester

Chemical Property of Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester

There total 3 articles about Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Phosphoric acid 1-cyano-2-{4-[cyano-(diethoxy-phosphoryloxy)-methyl-methyl]-benzyl}-cyclopentyl ester diethyl ester → Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester (96824-29-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; under 2206.5 Torr; Yield given;

Reference yield:

2-benzylcyclopentanone (2867-63-2) → Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester (96824-29-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / AlCl₃

2: tetrahydrofuran / Ambient temperature

3: H₂ / Pd/C / ethyl acetate / 2206.5 Torr

With aluminium trichloride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;

Reference yield:

2-(4-Acetyl-benzyl)-cyclopentanone (96824-28-1) → Phosphoric acid 1-cyano-2-[4-(cyano-methyl-methyl)-benzyl]-cyclopentyl ester diethyl ester (96824-29-2)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / Ambient temperature

2: H₂ / Pd/C / ethyl acetate / 2206.5 Torr

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;

upstream raw materials:

2-benzylcyclopentanone

2-(4-Acetyl-benzyl)-cyclopentanone

Downstream raw materials:

loxoprofen

Refernces