(2,2-Diethoxyethoxy)benzene

Base Information

• Chemical Name: (2,2-Diethoxyethoxy)benzene
• CAS No.: 32438-31-6
• Molecular Formula: C12H18 O3
• Molecular Weight: 210.273
• Hs Code.: 2911000000
• European Community (EC) Number: 251-041-8
• NSC Number: 67872
• UNII: EA07RN0YEL
• DSSTox Substance ID: DTXSID0067682
• Nikkaji Number: J319.383G
• Wikidata: Q81994321
• Mol file: 32438-31-6.mol

Synonyms:(2,2-Diethoxyethoxy)benzene;32438-31-6;Phenoxyacetaldehyde diethyl acetal;2,2-diethoxyethoxybenzene;Phenoxy-acetaldehyde diethyl acetal;Benzene, (2,2-diethoxyethoxy)-;Acetaldehyde, phenoxy-, diethyl acetal;2-phenoxyacetaldehyde diethyl acetal;EA07RN0YEL;EINECS 251-041-8;NSC 67872;NSC-67872;AI3-05965;UNII-EA07RN0YEL;Benzene,2-diethoxyethoxy)-;NCIOpen2_003387;2,2-Diethoxyethoxy-benzene,;SCHEMBL1193076;Phenoxyacetaldehyde diethylacetal;DTXSID0067682;NSC67872;Phenoxy-acetaldehyde, diethyl acetal;MFCD00272279;AKOS009157619;(2,2-Diethoxyethoxy)benzene, AldrichCPR;ETHANE, 1,1-DIETHOXY-2-PHENOXY-;BB 0220679;CS-0230110;FT-0677875;EN300-102331;Z1142694074

Chemical Property of (2,2-Diethoxyethoxy)benzene

Chemical Property:

• Vapor Pressure: 0.00361mmHg at 25°C
• Boiling Point: 290.4°Cat760mmHg
• Flash Point: 96.4°C
• PSA: 27.69000
• Density: 1.005g/cm³
• LogP: 2.46450
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 210.125594432
• Heavy Atom Count: 15
• Complexity: 138

Purity/Quality:

99% ^*data from raw suppliers

Phenoxy-acetaldehyde diethyl acetal ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(COC1=CC=CC=C1)OCC

Technology Process of (2,2-Diethoxyethoxy)benzene

There total 6 articles about (2,2-Diethoxyethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

chloroacetaldehyde diethyl acetal (621-62-5) + phenol (108-95-2,27073-41-2) → (2,2-diethoxy-ethoxy)-benzene (32438-31-6)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 175 ℃; for 1h; Microwave irradiation;

Reference yield: 96.0%

Bromoacetaldehyde diethyl acetal (2032-35-1) + phenol (108-95-2,27073-41-2) → (2,2-diethoxy-ethoxy)-benzene (32438-31-6)

Guidance literature:

With potassium carbonate; In acetone; for 18h; Reflux;

Reference yield:

sodium phenoxide (139-02-6) + chloroacetaldehyde diethyl acetal (621-62-5) → (2,2-diethoxy-ethoxy)-benzene (32438-31-6)

Guidance literature:

With ethanol; at 160 ℃;

upstream raw materials:

sodium phenoxide

Bromoacetaldehyde diethyl acetal

phenol

chloroacetaldehyde diethyl acetal

Downstream raw materials:

2-(3,5-dimethylphenyl)benzofuran

2-(2'-chlorophenyl)benzo[b]furan

2-(3-chlorophenyl)benzo[b]furan

2‐m‐tolylbenzofuran

Refernces

• 1、 -. "COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF". Paragraph 0249-0250. . Retrieved 2020/07/07.
• 2、 Fang, Huaquan,Guo, Le,Zhang, Yuxuan,Yao, Wubing,Huang, Zheng. "A Pincer Ruthenium Complex for Regioselective C-H Silylation of Heteroarenes". supporting information. p. 5624 - 5627. Retrieved 2016/11/17.