PALMITIC ACID SODIUM SALT

Base Information

• Chemical Name: PALMITIC ACID SODIUM SALT
• CAS No.: 408-35-5
• Molecular Formula: C16H32NaO2
• Molecular Weight: 278.411
• Hs Code.: 29157000
• Mol file: 408-35-5.mol

Synonyms:Hexadecanoicacid, sodium salt (9CI);Palmitic acid, sodium salt (8CI);C-Lube 16;NonsoulPN 1;PN 1;Sodium hexadecanoate;Sodium palmitate;Sodiumpentadecanecarboxylate;

Chemical Property of PALMITIC ACID SODIUM SALT

Chemical Property:

• Appearance/Colour: white powder
• Melting Point: 283-290 °C(lit.)
• Boiling Point: 340.6 °C at 760 mmHg
• Flash Point: 154.1 °C
• PSA: 40.13000
• LogP: 4.21760
• Storage Temp.: 2-8°C
• Solubility.: very faint turbidity in hot EtOH50vol%
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 14
• Exact Mass: 279.22999954
• Heavy Atom Count: 19
• Complexity: 178

Purity/Quality:

99.9% ^*data from raw suppliers

Sodium Palmitate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 22-24/25-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC(=O)O.[Na]
• Uses: Sodium palmitate (PA) has been used:to induce inflammation and thrombosis pathway in murine macrophage cell line RAW 264.7 cell line by activating reactive oxygen species (ROS) production, Janus-kinase (JNK) signalling and release of histone H3 by western blotting and cell viability by MTT assayto induce lipogenesis in AML12 cells and primary hepatocytes to analyse the effect of irisin on PA induced lipogenesis and related signal pathways by western blot analysis and quantitative PCR analysisas a component in free fatty acid mixture to induce cellular steatosis in HepG2 cell lines and determination of lipid accumulation by Oil-Red-O staining Sodium Palmitate is the sodium salt of palmitic acid. It functions as a binder, emulsifier, and anticaking agent. Polymerization catalyst for synthetic rubbers, laundry and toilet soaps, detergents, cosmetics, pharmaceuticals, printing inks, and as an emulsi- fier.

Technology Process of PALMITIC ACID SODIUM SALT

There total 5 articles about PALMITIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-hexadecylcarboxylic acid (57-10-3) → sodium palmitate (408-35-5)

Guidance literature:

With sodium hydroxide; In water; at 60 - 80 ℃;

DOI:10.13005/ojc/320404

Reference yield:

p-toluenesulfonic acid + 8-chloro-11-[4-(2-ethoxyethanol)-1-piperazinyl]-5H-dibenzo[b,e][1,4]diazepine + sodium carbonate (497-19-8) + 1-hexadecylcarboxylic acid (57-10-3) → sodium palmitate (408-35-5) + hexadecanoic acid 2-{2-[4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-piperazin-1-yl]-ethoxy}-ethyl ester (68465-70-3)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene;

Reference yield:

4-nitrophenyl palmitate (1492-30-4) → sodium palmitate (408-35-5) + 4-nitrophenol sodium salt (824-78-2)

Guidance literature:

With buffer (0.05 M H₂PO₄^-/HPO₄^2-); sodium chloride; In 1,4-dioxane; methanol; at 30 ℃; Rate constant; pH 8;

DOI:10.1021/ja961505l

upstream raw materials:

sodium formate

1-hexadecylcarboxylic acid

4-nitrophenyl palmitate

2,5-dimethylphenacyl palmitate

Downstream raw materials:

hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester

glyceroltripalmitate

palmitone

palmitic anhydride

Refernces

• 1、 Glushko,Anisimova,Blokhina. "The salts of fatty acids as precursors for preparation of silver nanoparticles in organic solvents". . p. 1759 - 1764. Retrieved 2016/10/24.
• 2、 Wang, Guang-Jia,Ye, Donghao,Fife, Wilmer K.. "Salt effects on solvolysis reactions of p-nitrophenyl alkanoates catalyzed by 4-(dialkylamino)pyridine-functionalized polymer in buffered water and aqueous methanol solutions". . p. 12536 - 12540. Retrieved 2007/10/03.