2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane

Base Information

• Chemical Name: 2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane
• CAS No.: 1346142-27-5
• Molecular Formula: C₃₇H₁₆F₂₀N₄O₂
• Molecular Weight: 928.528
• Mol file: 1346142-27-5.mol

Synonyms:2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane

Chemical Property of 2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane

There total 3 articles about 2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

heptafluorobutyric anhydride (336-59-4) + C29H22F6N4O2 → 2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane (1346142-27-5)

Guidance literature:

heptafluorobutyric anhydride; C₂₉H₂₂F₆N₄O₂; With pyridine; In toluene; at 0 - 20 ℃; for 48h; Inert atmosphere;

With sodium carbonate; In dichloromethane; water;

DOI:10.1016/j.ejmech.2011.09.046

Reference yield:

4-(aminomethyl)pyridine (3731-53-1) → 2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane (1346142-27-5)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; triethylamine

2: pyridine / toluene / 48 h / 0 - 20 °C / Inert atmosphere

With pyridine; dmap; triethylamine; In toluene;

DOI:10.1016/j.ejmech.2011.09.046

Reference yield:

2,2-bis(4-chlorocarbonylphenyl)-hexafluoropropane (1102-92-7) → 2,2-bis[4-(5-heptafluoropropyl-4-(4-pyridyl)oxazol-2-yl)phenyl]hexafluoropropane (1346142-27-5)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; triethylamine

2: pyridine / toluene / 48 h / 0 - 20 °C / Inert atmosphere

With pyridine; dmap; triethylamine; In toluene;

DOI:10.1016/j.ejmech.2011.09.046

upstream raw materials:

4-(aminomethyl)pyridine

2,2-bis(4-chlorocarbonylphenyl)-hexafluoropropane

heptafluorobutyric anhydride

Refernces