methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate

Base Information

• Chemical Name: methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate
• CAS No.: 177583-36-7
• Molecular Formula: C₂₁H₂₅NO₄
• Molecular Weight: 355.434
• Mol file: 177583-36-7.mol

Synonyms:methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate

Chemical Property of methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate

There total 2 articles about methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylacrylate (1262296-30-9) → methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate (177583-36-7)

Guidance literature:

With tetraethylammonium chloride; triethylamine hydrochloride; In acetonitrile; Electrochemical reaction;

DOI:10.1016/j.tet.2010.10.087

Reference yield: 14.0%

→ methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate (177583-36-7)

Guidance literature:

Reference yield:

methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate (177583-36-7) → (S)-β,β-diphenyl-α-alanine (149597-92-2) + (2R)-3,3-diphenylalanine (149597-91-1)

Guidance literature:

methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate; With hydrogenchloride; water; for 5h; Heating / reflux;

With sodium hydroxide; water;

upstream raw materials:

methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylacrylate

Downstream raw materials:

(S)-β,β-diphenyl-α-alanine

(2R)-3,3-diphenylalanine

Refernces

• 1、 -. "NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID". Page/Page column 40. . Retrieved 2009/05/29.