Technology Process of 2-benzyl-1,1,3,3-tetraethyl-5,6-bis(hydroxymethyl)isoindoline
There total 5 articles about 2-benzyl-1,1,3,3-tetraethyl-5,6-bis(hydroxymethyl)isoindoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
diethyl ether;
for 72h;
Reflux;
DOI:10.1002/ejoc.200801255
- Guidance literature:
-
Multi-step reaction with 4 steps
1: acetic acid / 1.5 h / 120 °C
2: toluene; diethyl ether / 3 h / Reflux
3: sodium hydroxide; pyridine; potassium permanganate / water / 96 h / Reflux
4: lithium aluminium tetrahydride / diethyl ether / 72 h / Reflux
With
pyridine; potassium permanganate; lithium aluminium tetrahydride; acetic acid; sodium hydroxide;
In
diethyl ether; water; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: acetic acid / 1.5 h / 120 °C
2: toluene; diethyl ether / 3 h / Reflux
3: sodium hydroxide; pyridine; potassium permanganate / water / 96 h / Reflux
4: lithium aluminium tetrahydride / diethyl ether / 72 h / Reflux
With
pyridine; potassium permanganate; lithium aluminium tetrahydride; acetic acid; sodium hydroxide;
In
diethyl ether; water; toluene;
