Methandrostenolone

Base Information

• Chemical Name: Methandrostenolone
• CAS No.: 72-63-9
• Molecular Formula: C20H28O2
• Molecular Weight: 300.441
• Hs Code.: 29329970
• European Community (EC) Number: 200-787-2
• NSC Number: 51180,42722
• UNII: COZ1R7EOCC
• DSSTox Substance ID: DTXSID2023276
• Nikkaji Number: J5.252C
• Wikipedia: Metandienone
• Wikidata: Q417194
• NCI Thesaurus Code: C87589
• Metabolomics Workbench ID: 35321
• ChEMBL ID: CHEMBL1418176
• Mol file: 72-63-9.mol

Synonyms:Dehydromethyltestosterone;Dianabol;Metanabol;Metandienone;Methandienone;Methandrostenolone;Nerobol

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Methandrostenolone

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder
• Vapor Pressure: 1.87E-09mmHg at 25°C
• Melting Point: 165-166 °C
• Refractive Index: 1.572
• Boiling Point: 436.5 °C at 760 mmHg
• PKA: 15.12±0.60(Predicted)
• Flash Point: 186.2 °C
• PSA: 37.30000
• Density: 1.12 g/cm³
• LogP: 4.04530
• Storage Temp.: 2-8°C
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 300.208930132
• Heavy Atom Count: 22
• Complexity: 589

Purity/Quality:

Safty Information:

• Pictogram(s): F,T
• Hazard Codes: F,T
• Statements: 60-61-11-19-38
• Safety Statements: 53-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2(C)O)CCC4=CC(=O)C=CC34C
• Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CCC4=CC(=O)C=C[C@]34C
• Recent EU Clinical Trials: PHASE I/II CLINICAL TRIAL ON THE USE OF THE AMNIOTIC MEMBRANE FOR LARGE WOUND EPITHELIZATION
• Drug Interactions: When Metandienone is used with oxyphenbutazone, the blood concentration of oxyphenbutazone may increase.
• Therapeutic Function: Androgen, Anabolic

Technology Process of Methandrostenolone

There total 12 articles about Methandrostenolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.6%

methyl bromide (74-83-9) + Androsta-1,4-diene-3,17-dione (897-06-3) → metandienone (72-63-9)

Guidance literature:

methyl bromide; With magnesium; In tetrahydrofuran; at 40 - 45 ℃;

Androsta-1,4-diene-3,17-dione; In toluene; at 50 - 55 ℃;

Reference yield: 92.5%

methylene chloride (74-87-3) + Androsta-1,4-diene-3,17-dione (897-06-3) → metandienone (72-63-9)

Guidance literature:

methylene chloride; With magnesium; In tetrahydrofuran; at 30 - 35 ℃;

Androsta-1,4-diene-3,17-dione; In tetrahydrofuran; at 50 - 55 ℃;

Reference yield: 90.8%

Androsta-1,4-diene-3,17-dione (897-06-3) + methyl iodide (74-88-4) → metandienone (72-63-9)

Guidance literature:

methyl iodide; With magnesium; In diethyl ether; at 30 - 35 ℃;

Androsta-1,4-diene-3,17-dione; In benzene; at 50 - 55 ℃;

upstream raw materials:

methylene chloride

androsta-1,4-diene-3,17-dione

17-methyltestosterone

Androsta-1,4-diene-3,17-dione

Downstream raw materials:

17β-Hydroxy-3-oxo-17α-methyl-Δ^1,4,6-androstatrien

7β,17β,-dihydroxy-17α-methylandrost-1,4-dien-3-one

15β,17β-dihydroxy-17α-methylandrost-1,4-dien-3-one

17β-hydroxy-17α-methylandrost-1,4-dien-3,11-dione

Refernces

• 1、 -. "Preparation method of metandienone". Paragraph 0036-0056. . Retrieved 2019/03/06.
• 2、 -. "Method for preparing metandienone". Paragraph 0036-0042. . Retrieved 2019/03/06.