Trimethylsulfoxonium-d9 Iodide

Base Information

• Chemical Name: Trimethylsulfoxonium-d9 Iodide
• CAS No.: 23726-00-3
• Molecular Formula: C₃H₉OS*I
• Molecular Weight: 229.003
• Mol file: 23726-00-3.mol

Synonyms:<²H9>trimethylsulphoxonium iodide

Chemical Property of Trimethylsulfoxonium-d9 Iodide

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Trimethylsulfoxonium-d9 Iodide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (Trimethylsulfoxonium-d9 Iodide) Labelled Trimethylsulfoxonium Iodide (T797500). Used to synthesize methylene-transfer reagents that are used in the preparation of epoxides.

Technology Process of Trimethylsulfoxonium-d9 Iodide

There total 1 articles about Trimethylsulfoxonium-d9 Iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethylsulfoxide-d6 (2206-27-1) + methyl iodide (74-88-4) → methanol (67-56-1) + Dimethyl ether (115-10-6,157621-61-9) + dimethyl ether-d6 (17222-37-6) + dimethylsulfoxide-d5 + Methyl(trideuteriomethyl)sulfid (4752-12-9) + dimethyl sulfide-d6 (926-09-0) + dimethylsulphoxide-d3 (21892-74-0) + <2H9>trimethylsulphoxonium iodide (23726-00-3) + trimethylsulphoxonium-d6 iodide (78730-02-6)

Guidance literature:

In 1,4-dioxane; at 21.84 ℃; Time; Sealed tube;

DOI:10.1080/17415993.2015.1066376

Reference yield: 99.0%

<2H9>trimethylsulphoxonium iodide (23726-00-3) + diethyl 2-phenylmalonate (83-13-6) → diethyl 2-(methyl-d3)-2-phenylmalonate

Guidance literature:

diethyl 2-phenylmalonate; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.5h; Sealed tube;

<²H9>trimethylsulphoxonium iodide; In tetrahydrofuran; mineral oil; at 80 ℃; for 8h; Sealed tube;

DOI:10.1021/acs.orglett.8b03641

Reference yield: 99.0%

methyl 3-hydroxybenzoate (19438-10-9) + <2H9>trimethylsulphoxonium iodide (23726-00-3) → methyl 3-(methoxy-d3)benzoate

Guidance literature:

With potassium carbonate; at 65 ℃; for 18h; Sealed tube;

DOI:10.1021/acs.orglett.8b03641

upstream raw materials:

dimethylsulfoxide-d6

methyl iodide

Downstream raw materials:

<4,4-²H2>-4a,6-diphenyl-4,4a-dihydrocyclopropa<3,4>cyclohepta<1,2-c>thiophen-5(3bH)-one

trans-2-<2-(2'-methyl-phenyl)-3,3-d2-cyclopropyl>-4-oxo-3-propyl-4H-1-benzopyran-6-carboxylic acid, methyl ester

diethyl 2,2-dideuterio-3-phenylcyclopropane-1,1-dicarboxylate

(3S,6S)-4,7-bis(4-methoxybenzyl)-[1,1-2H]-6-isopropyl-4,7-diazaspiro[2.5]octane-5,8-dione

Refernces