1-bromo-1,1-difluoro-propane

Base Information

• Chemical Name: 1-bromo-1,1-difluoro-propane
• CAS No.: 420-89-3
• Molecular Formula: C₃H₅BrF₂
• Molecular Weight: 158.974
• Mol file: 420-89-3.mol

Synonyms:1-bromo-1,1-difluoro-propane

Chemical Property of 1-bromo-1,1-difluoro-propane

Chemical Property:

• Boiling Point: 46-46.5 °C
• Density: 1.555±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-1,1-difluoropropane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-bromo-1,1-difluoro-propane

There total 2 articles about 1-bromo-1,1-difluoro-propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-difluoropropene (430-63-7) → 1-bromo-1,1-difluoro-propane (420-89-3)

Guidance literature:

With aluminum tri-bromide; hydrogen bromide;

DOI:10.1039/jr9530003565

Reference yield:

1,1-difluoropropene (430-63-7) + hydrogen bromide (10035-10-6,12258-64-9) + aluminium bromide (7727-15-3) → 1-bromo-1,1-difluoro-propane (420-89-3)

Guidance literature:

DOI:10.1039/jr9530003565

Reference yield: 52.0%

1-bromo-1,1-difluoro-propane (420-89-3) + vinyl phenyl ether (766-94-9) + 4-biphenylylmagnesium bromide (3315-91-1) → 4-(3,3-difluoro-1-phenoxypentyl)-1,1'-biphenyl

Guidance literature:

1-bromo-1,1-difluoropropane; vinyl phenyl ether; With iron(III)-acetylacetonate; 1,2-bis-(dicyclohexylphosphino)ethane; In tetrahydrofuran; at 20 ℃; for 0.0833333h; Inert atmosphere; Sealed tube;

4-biphenylylmagnesium bromide; In tetrahydrofuran; at 0 ℃; for 1.16667h; regioselective reaction; Inert atmosphere;

DOI:10.1039/d1cc04619e

upstream raw materials:

1,1-difluoropropene

hydrogen bromide

aluminium bromide

Downstream raw materials:

1,1,1-trifluoropropane