2-phenyl-2,3-dihydroinden-1-one

Base Information

• Chemical Name: 2-phenyl-2,3-dihydroinden-1-one
• CAS No.: 16619-12-8
• Molecular Formula: C15H12 O
• Molecular Weight: 208.26
• Mol file: 16619-12-8.mol

Synonyms:1-Indanone,2-phenyl- (6CI,7CI,8CI); 2-Phenyl-1-indanone; NSC 255087

Chemical Property of 2-phenyl-2,3-dihydroinden-1-one

Chemical Property:

• Vapor Pressure: 0.000126mmHg at 25°C
• Melting Point: 77.5°C
• Refractive Index: 1.5361 (estimate)
• Boiling Point: 334.7°Cat760mmHg
• Flash Point: 144.3°C
• PSA: 17.07000
• Density: 1.162g/cm³
• LogP: 3.20920
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

2-Phenyl-2,3-dihydro-1H-inden-1-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 2-phenyl-2,3-dihydroinden-1-one

There total 53 articles about 2-phenyl-2,3-dihydroinden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,2-diphenylprop-2-en-1-one (4452-11-3) → 2-phenyl-indan-1-one (16619-12-8)

Guidance literature:

With trifluorormethanesulfonic acid; at 0 ℃; for 5h; further reagents: TFSA(6percent)+TFA(94percent), TFA;

DOI:10.1021/ja971100g

Reference yield: 92.0%

1-trimethylsilyloxy-3H-indene (31928-64-0) → 2-phenyl-indan-1-one (16619-12-8)

Guidance literature:

In tetrahydrofuran; at -40 - 20 ℃; for 0.2h;

DOI:10.1021/ja030150k

Reference yield: 89.0%

diphenyl acetylene (501-65-5) → 2-phenyl-indan-1-one (16619-12-8)

Guidance literature:

With water; 2; In tetrahydrofuran; at 220 ℃; for 4h; under 76000.1 Torr;

DOI:10.1246/cl.1988.901

upstream raw materials:

2,3-diphenylpropanoic acid

2,3-diphenylpropionyl chloride

2-phenyl-1H-inden-1-one

2-phenyl-2-phenylthioindan-1-one

Downstream raw materials:

2-Phenyl-3-<4-(2-diaethylamino-aethoxy)-phenyl>-inden

benzo[a]fluorene

3-methyl-2-phenyl-1H-indene

2-phenyl-1H-inden-3-yl acetate

Refernces

• 1、 Chen, Zi-Hao,Sun, Rui-Ze,Yao, Fei,Hu, Xu-Dong,Xiang, Long-Xue,Cong, Hengjiang,Liu, Wen-Bo. "Enantioselective Nickel-Catalyzed Reductive Aryl/Alkenyl-Cyano Cyclization Coupling to All-Carbon Quaternary Stereocenters". supporting information. p. 4776 - 4782. Retrieved 2022/03/27.
• 2、 Yuan, Jing,Liu, Chong,Chen, Yan,Zhang, Zhenfeng,Yan, Deyue,Zhang, Wanbin. "Rhodium-catalyzed intramolecular hydroacylation of 1,2-disubstituted alkenes for the synthesis of 2-substituted indanones". . p. 269 - 277. Retrieved 2018/12/05.