Technology Process of 3-[(2-cyclohexylethyl)amino]-4-nitrobenzonitrile
There total 5 articles about 3-[(2-cyclohexylethyl)amino]-4-nitrobenzonitrile which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium carbonate;
at 150 ℃;
for 18h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: oxalyl dichloride / N,N-dimethyl-formamide / tetrahydrofuran / 1 h / 0 - 20 °C
1.2: 0.17 h / 0 °C
2.1: triethylamine; trifluoroacetic anhydride / tetrahydrofuran / 1.5 h
3.1: potassium carbonate / 18 h / 150 °C
With
oxalyl dichloride; potassium carbonate; triethylamine; trifluoroacetic anhydride;
N,N-dimethyl-formamide;
In
tetrahydrofuran;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 118 h / 5 - 20 °C
2: hydrazine / methanol / 3 h / Heating / reflux
3: potassium carbonate / 18 h / 150 °C
With
di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine; hydrazine;
In
tetrahydrofuran; methanol;
