177476-75-4

Basic information

• Product Name: BENZONITRILE, 3-METHOXY-4-NITRO-
• Synonyms: BENZONITRILE, 3-METHOXY-4-NITRO-;3-Methoxy-4-nitrobenzenecarbonitrile;3-Methoxy-4-nitrobenzonitrile;5-Cyano-2-nitroanisole, 4-Cyano-2-methoxynitrobenzene
• CAS NO: 177476-75-4
• Molecular Formula: C₈H₆N₂O₃
• Molecular Weight: 178.146
• Mol File: 177476-75-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 125-126°
• Boiling Point: 344.4 °C at 760 mmHg
• Flash Point: 162.1 °C
• Appearance: /
• Density: 1.32 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: BENZONITRILE, 3-METHOXY-4-NITRO-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZONITRILE, 3-METHOXY-4-NITRO-(177476-75-4)
• EPA Substance Registry System: BENZONITRILE, 3-METHOXY-4-NITRO-(177476-75-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 177476-75-4(Hazardous Substances Data)

Usage

General Description

Benzonitrile, 3-methoxy-4-nitro-, also known as 3-Methoxy-4-nitrobenzonitrile, is a chemical compound with the molecular formula C8H6N2O3. It is a yellow to brown crystalline solid that is used in the synthesis of pharmaceuticals and agrochemicals. Benzonitrile, 3-methoxy-4-nitro- is also used as an intermediate in the production of dyes and other organic compounds. It is considered to be a hazardous substance and should be handled and stored with care due to its potential toxicity and environmental impact.

Upstream product

• 218632-01-0 3-fluoro-4-nitrobenzonitrile 
• 124-41-4 sodium methylate 
• 67579-92-4 3-methoxy-4-nitrobenzoic acid chloride 
• 5081-36-7 3-methoxy-4-nitrobenzoic acid 
• 92241-87-7 3-methoxy-4-nitrobenzamide 
• 1527-89-5 3-methoxybenzonitrile 

Downstream Products

• 64910-48-1 3-N-(methylamino)-4-nitrobenzonitrile 
• 53484-14-3 3-methyl-3H-benzoimidazole-5-carbonitrile 
• 6595-25-1 1.2-Dimethyl-6-benzimidazol-carbonitril 
• 864275-07-0 4-amino-3-(cyclopropylmethylamino)benzonitrile 
• 864274-02-2 1-methyl-1H-1,2,3-benzotriazole-6-carbonitrile 
• 181867-19-6 1-methyl-1H-benzo[d]imidazole-6-carbaldehyde 
• 864274-81-7 4-amino-3-[(2-cyclopentylethyl)amino]benzonitrile 
• 864275-10-5 4-amino-3-(cyclopentylamino)benzonitrile 

Relevant articles and documents

Substituted Heteroaryl Spiropyrrolidine MDM2 Antagonists

There are provided compounds of the general formula wherein A, B, V, W, R1, R2, R3, R3, and R4, are as described herein and enantiomers and pharmaceutically acceptable salts thereof. The compounds are useful as anticancer agents.

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There are provided compounds of the formula (I) wherein X, Y and R1 to R8 are as described herein, their enantiomers and pharmaceutically acceptable salts and esters, as well as processes for making these compounds and medicaments containing them.

2,4-DI(AMINOPHENYL) PYRIMIDINES AS PLK INHIBITORS

The invention relates to compounds of general formula (1), wherein A, W, X, Y, Z, Ra, Rb, Rc, R1, and R3 are defined as indicated in claim 1. Said compounds are used for the treatment of diseases characterized by excessive or anomalous cell proliferation. Also disclosed is the use of the inventive compounds for producing a medicament having said properties.