Oxine-copper

Base Information

• Chemical Name: Oxine-copper
• CAS No.: 10380-28-6
• Molecular Formula: C₁₈H₁₂CuN₂O₂
• Molecular Weight: 351.851
• Hs Code.: 29334900
• European Community (EC) Number: 233-841-9
• ICSC Number: 0756
• UN Number: 3077
• UNII: W8YEE02477
• Nikkaji Number: J124.112E
• Wikidata: Q2629981
• Mol file: 10380-28-6.mol

Synonyms:bis(8-quinolinolato)copper(II);copper oxinate;copper(II) oxinate;Cu 8Q;cupric 8-quinolinoxide

Chemical Property of Oxine-copper

Chemical Property:

• Appearance/Colour: Yellow to greenish powder
• Melting Point: 240 ºC
• Boiling Point: 267 ºC at 760 mmHg
• Flash Point: 143.1 ºC
• PSA: 44.24000
• Density: 1.68 g/cm³
• LogP: 4.15330
• Storage Temp.: 0-6°C
• Water Solubility.: Insoluble in water
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 351.019475
• Heavy Atom Count: 23
• Complexity: 138

Purity/Quality:

98.5% Min. ^*data from raw suppliers

bis(8-Quinolinolato-κN1,κO8)-Copper(>90%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Pesticides -> Fungicides
• Canonical SMILES: C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]
• Inhalation Risk: A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
• Effects of Short Term Exposure: The substance is irritating to the eyes and possibly the respiratory tract.
• Uses: Fungicide and mildew-proofing of fabrics, analysis for copper. bis(8-Quinolinolato-κN1,κO8)-Copper is a disinfectant for vegetables. High polarity pesticide.

Technology Process of Oxine-copper

There total 26 articles about Oxine-copper which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

8-quinolinol (148-24-3,24804-14-6) + copper(II) acetate monohydrate (6046-93-1) → bis(8-hydroxyquinolato)copper(II) (10380-28-6,60208-38-0)

Guidance literature:

In neat (no solvent, solid phase); solid state react. of CuAc2 with 8-hydroxyquinoline; elem. anal.;

DOI:10.1006/jssc.1993.1305

Reference yield: 77.0%

8-quinolinol (148-24-3,24804-14-6) + copper(II) choride dihydrate → bis(8-hydroxyquinolato)copper(II) (10380-28-6,60208-38-0)

Guidance literature:

In methanol; water; for 0.5h;

DOI:10.1021/jm301053a

Reference yield: 28.35%

8-quinolinol (148-24-3,24804-14-6) + copper (12775-96-1,15158-11-9,15721-63-8,16941-75-6,17493-86-6,19498-52-3,20499-83-6,20499-84-7,20499-85-8,20499-86-9,20573-10-8,20573-11-9,21595-51-7,21595-52-8,22206-52-6,26445-28-3,28959-95-7,37362-93-9,39417-05-5,54603-16-6,54603-23-5,54603-32-6,54603-40-6,54603-48-4,54603-81-5,54603-89-3,56316-56-4,95985-91-4,122297-32-9,7440-50-8) → bis(8-hydroxyquinolato)copper(II) (10380-28-6,60208-38-0) + hydrogen (1333-74-0)

Guidance literature:

In neat (no solvent); simultanous thermal vaporisation (1E-4 mmHg); vibrational spectroscopy;

upstream raw materials:

8-quinolinol

copper

copper diacetate

copper(II) acetate monohydrate

Downstream raw materials:

Cu(8-HQ)

(tetraphenylporphyrin)copper(II)

Refernces

• 1、 Zaki, Mohamed Tarek Mohamed,Hanna, Wageh Georgy,Fawzy, Mohamed Hossam. "Conductometric Determination of Some Metal Ions Using Oxine as Reagent". . p. 1761 - 1766. Retrieved 1988.
• 2、 Kotlyar, S. S.,Yanishpol'skii, V. V.,Tertykh, V. A.. "". . . Retrieved 1989.
• 3、 Chatterjee, K. K.. "". . p. 232 - 235. Retrieved 1959.
• 4、 Stevens, H. M.. "". . p. 435 - 438. Retrieved 1957.
• 5、 Clifford,Sargent. "". . p. 4041. Retrieved 1957.
• 6、 Kolhe Nitin,Jadhav Shridhar,Shaikh Sajid,Takate Sushama,Aware Dinkar. "Nanocrystalline mixed ligand complexes of Cu (II), Ni (II), Co(II) with N, O donor ligands: Synthesis, characterization, and antimicrobial activity". . p. 2999 - 3013. Retrieved 2016.
• 7、 Shiraiwa, Tadashi,Fukuoka, Hirofumi,Yoshida, Masahiro,Kurokawa, Hidemoto. "Optical Resolution of DL-Alanine by Formation of Ternary Copper(II) Complexes with L-Isoleucine". . p. 1675 - 1676. Retrieved 1984.
• 8、 Wehbe, Mohamed,Lo, Cody,Leung, Ada W. Y.,Dragowska, Wieslawa H.,Ryan, Gemma M.,Bally, Marcel B.. "Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status". . p. 682 - 690. Retrieved 2017/10/06.