Dimethindene

Base Information

• Chemical Name: Dimethindene
• CAS No.: 5636-83-9
• Molecular Formula: C20H24N2
• Molecular Weight: 292.424
• European Community (EC) Number: 227-083-8
• UNII: 661FH77Z3P
• DSSTox Substance ID: DTXSID9022942
• Nikkaji Number: J8.041A
• Wikipedia: Dimetindene
• Wikidata: Q426070
• NCI Thesaurus Code: C83675
• Pharos Ligand ID: QJ7SXS4TSLCZ
• Metabolomics Workbench ID: 43718
• ChEMBL ID: CHEMBL22108
• Mol file: 5636-83-9.mol

Synonyms:Dimethindene;Dimethindene Maleate;Dimethpyrindene;Dimetindene;Fenistil;Forhistal;Maleate, Dimethindene

Chemical Property of Dimethindene

Chemical Property:

• Vapor Pressure: 3.85E-07mmHg at 25°C
• Refractive Index: 1.587
• Boiling Point: 416.3 °C at 760 mmHg
• PKA: 9.58±0.28(Predicted)
• Flash Point: 205.6 °C
• PSA: 16.13000
• Density: 1.065 g/cm³
• LogP: 4.14670
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: 238.6mg/L(37 oC)
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 292.193948774
• Heavy Atom Count: 22
• Complexity: 399

Purity/Quality:

98%Min ^*data from raw suppliers

Dimethindene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C
• Recent ClinicalTrials: Placebo Effect in the Treatment of Atopic Dermatitis
• Recent EU Clinical Trials: Nutzen des Placeboeffektes bei atopischer Dermatitis - Steigerung der pharmakologischen Wirkung bei Juckreiz durch Klassische Konditionierung und Erwartungsprozesse: Eine randomisierte kontrollierte Studie
• Therapeutic Function: Antihistaminic

Technology Process of Dimethindene

There total 1 articles about Dimethindene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Dimetindene (5636-83-9)

Guidance literature:

Indanon II, 1-(2-Pyridyl)-ethyl-MgBr;

Reference yield:

Dimetindene (5636-83-9) → (S)-(+)-dimethindene (121367-05-3)

Guidance literature:

Downstream raw materials:

(S)-(+)-dimethindene