N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid

Base Information

• Chemical Name: N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid
• CAS No.: 39628-26-7
• Molecular Formula: C₁₄H₁₉NO₅
• Molecular Weight: 281.309
• Mol file: 39628-26-7.mol

Synonyms:N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid

Chemical Property of N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid

There total 4 articles about N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N-(3,4-dimethoxyphenethyl)-α-bromoacetamide (56997-75-2) + acetic acid (64-19-7,77671-22-8) → N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid (39628-26-7)

Guidance literature:

With potassium carbonate; In tetrahydrofuran;

DOI:10.1002/asia.201403361

Reference yield:

2-nitro-1-(3,4-dimethoxyphenyl)ethanol (39220-86-5) → N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid (39628-26-7)

Guidance literature:

Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride

2: potassium carbonate

3: potassium carbonate / tetrahydrofuran

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran;

DOI:10.1002/asia.201403361

Reference yield:

3,4-dimethoxy-benzaldehyde (120-14-9) → N-(3,4-Dimethoxy-β-phenylaethyl)-acetoxyacetamid (39628-26-7)

Guidance literature:

Multi-step reaction with 4 steps

1: ethylenediamine diacetic acid

2: lithium aluminium tetrahydride

3: potassium carbonate

4: potassium carbonate / tetrahydrofuran

With lithium aluminium tetrahydride; potassium carbonate; ethylenediamine diacetic acid; In tetrahydrofuran;

DOI:10.1002/asia.201403361

upstream raw materials:

N-(3,4-dimethoxyphenethyl)-α-bromoacetamide

acetic acid

2-nitro-1-(3,4-dimethoxyphenyl)ethanol

3,4-dimethoxy-benzaldehyde

Refernces