Technology Process of 2-<2-(4,5-diphenyl-2-oxazolyl)ethyl>-1-(N-allylcarbamoylmethyl)azetidinone
There total 5 articles about 2-<2-(4,5-diphenyl-2-oxazolyl)ethyl>-1-(N-allylcarbamoylmethyl)azetidinone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
water; ethylene glycol; glycerol;
at 25 ℃;
for 2.5h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) carbonyldiimidazole / 1.) THF, 25 deg C, 6 h, 2.) 25 deg C
2: 80 percent / ammonium acetate, acetic acid / benzene / 3 h / Heating
3: 87 percent / concd. HCl, NaBH3CN, Bromokresol Green / tetrahydrofuran; ethanol / 0 °C
4: 87.8 percent / NaOH / methanol / 4 h / Heating
5: 74 percent / H2O; ethane-1,2-diol; glycerol / 2.5 h / 25 °C
With
ammonium acetate; hydrogenchloride; sodium hydroxide; bromocresol green; sodium cyanoborohydride; acetic acid; 1,1'-carbonyldiimidazole;
In
tetrahydrofuran; methanol; ethanol; water; ethylene glycol; glycerol; benzene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 87.8 percent / NaOH / methanol / 4 h / Heating
2: 74 percent / H2O; ethane-1,2-diol; glycerol / 2.5 h / 25 °C
With
sodium hydroxide;
In
methanol; water; ethylene glycol; glycerol;