5-ALPHA-PREGNAN-3-BETA, 11-BETA, 20-BETA, 21-TETROL

Base Information

• Chemical Name: 5-ALPHA-PREGNAN-3-BETA, 11-BETA, 20-BETA, 21-TETROL
• CAS No.: 7285-27-0
• Molecular Formula: C₂₁H₃₆O₄
• Molecular Weight: 352.514
• Mol file: 7285-27-0.mol

Synonyms:5a-Pregnane-3b,11b,20b,21-tetrol (7CI,8CI); 3b,5a,20b-Hexahydrocorticosterone

Chemical Property of 5-ALPHA-PREGNAN-3-BETA, 11-BETA, 20-BETA, 21-TETROL

Chemical Property:

• Vapor Pressure: 2.17E-13mmHg at 25°C
• Boiling Point: 528.8°C at 760 mmHg
• Flash Point: 238°C
• PSA: 43.37000
• Density: 1.18g/cm³
• LogP: 1.18670

Purity/Quality:

97% ^*data from raw suppliers

5-ALPHA-PREGNAN-3-BETA,11-BETA,20-BETA,21-TETROL 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-ALPHA-PREGNAN-3-BETA, 11-BETA, 20-BETA, 21-TETROL

There total 5 articles about 5-ALPHA-PREGNAN-3-BETA, 11-BETA, 20-BETA, 21-TETROL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Corticosterone (50-22-6) → (20Ξ)-5α-pregnanetetrol-(3β,11β,20,21) (6815-98-1,6815-99-2,7285-27-0,7791-41-5,10417-87-5,14149-84-9,32040-50-9,53494-74-9,53494-76-1,53494-77-2,53494-78-3)

Guidance literature:

With ethanol; acetic acid; platinum; Hydrogenation_.Hydrierung des Reaktionsprodukts in Methanol an Raney-Nickel bei 80grad/70 at;

DOI:10.1557/mrs2001.93

Reference yield:

5α-pregnane-11β,21-diol-3,20-dione (298-25-9) → (20Ξ)-5α-pregnanetetrol-(3β,11β,20,21) (6815-98-1,6815-99-2,7285-27-0,7791-41-5,10417-87-5,14149-84-9,32040-50-9,53494-74-9,53494-76-1,53494-77-2,53494-78-3)

Guidance literature:

With ethanol; platinum; Hydrogenation;

DOI:10.1007/BF03192451

Reference yield:

ethanol (64-17-5) + 5α-pregnane-11β,21-diol-3,20-dione (298-25-9) → (20Ξ)-5α-pregnanetetrol-(3β,11β,20,21) (6815-98-1,6815-99-2,7285-27-0,7791-41-5,10417-87-5,14149-84-9,32040-50-9,53494-74-9,53494-76-1,53494-77-2,53494-78-3)

Guidance literature:

Hydrogenation;

DOI:10.1007/BF03192451

upstream raw materials:

Corticosterone

5α-pregnane-11β,21-diol-3,20-dione

ethanol

acetic acid

Downstream raw materials:

5α-pregnane-3β,11β,20-triol