bis(2-fluorophenyl)iodonium tetrafluoroborate

Base Information

• Chemical Name: bis(2-fluorophenyl)iodonium tetrafluoroborate
• CAS No.: 1034926-54-9
• Molecular Formula: BF₄*C₁₂H₈F₂I
• Molecular Weight: 403.901
• Mol file: 1034926-54-9.mol

Synonyms:bis(2-fluorophenyl)iodonium tetrafluoroborate

Chemical Property of bis(2-fluorophenyl)iodonium tetrafluoroborate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of bis(2-fluorophenyl)iodonium tetrafluoroborate

There total 2 articles about bis(2-fluorophenyl)iodonium tetrafluoroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-Fluoro-2-iodobenzene (348-52-7) + o-fluorophenylboronic acid (1993-03-9) → bis(2-fluorophenyl)iodonium tetrafluoroborate (1034926-54-9)

Guidance literature:

1-Fluoro-2-iodobenzene; With boron trifluoride diethyl etherate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 0.5h;

o-fluorophenylboronic acid; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1021/ol200265t

Reference yield: 85.0%

1-Fluoro-2-iodobenzene (348-52-7) + boron trifluoride diethyl etherate (109-63-7) + o-fluorophenylboronic acid (1993-03-9) → bis(2-fluorophenyl)iodonium tetrafluoroborate (1034926-54-9)

Guidance literature:

1-Fluoro-2-iodobenzene; boron trifluoride diethyl etherate; With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 0.5h; Sealed tube;

o-fluorophenylboronic acid; In dichloromethane; at 20 ℃; for 0.25h; Sealed tube;

DOI:10.1002/anie.201603175

Reference yield: 99.0%

bis(2-fluorophenyl)iodonium tetrafluoroborate (1034926-54-9) + Acetanilid (103-84-4) → N-phenyl-2-fluoroacetanilide (32090-98-5)

Guidance literature:

With sodium hydride; In toluene; mineral oil; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.orglett.5b01079

upstream raw materials:

1-Fluoro-2-iodobenzene

o-fluorophenylboronic acid

boron trifluoride diethyl etherate

Downstream raw materials:

1-fluoro-2-[(trifluoromethyl)sulfonyl]benzene

1-fluoro-2-(2-methoxy-2-phenylethyl)benzene

1-(2-fluorophenyl)-2-phenyl-2-propanol

1-Fluoro-2-iodobenzene

Refernces

• 1、 Reitti, Marcus,Villo, Piret,Olofsson, Berit. "One-Pot C?H Functionalization of Arenes by Diaryliodonium Salts". supporting information. p. 8928 - 8932. Retrieved 2016/07/26.
• 2、 Tinnis, Fredrik,Stridfeldt, Elin,Lundberg, Helena,Adolfsson, Hans,Olofsson, Berit. "Metal-free n -arylation of secondary amides at room temperature". supporting information. p. 2688 - 2691. Retrieved 2015/06/16.