Triphenylformazan

Base Information

• Chemical Name: Triphenylformazan
• CAS No.: 531-52-2
• Molecular Formula: C19H16 N4
• Molecular Weight: 300.363
• Hs Code.: 2928000090
• European Community (EC) Number: 208-509-1
• Mol file: 531-52-2.mol

Synonyms:1,3,5-triphenylformazan

Chemical Property of Triphenylformazan

Chemical Property:

• Appearance/Colour: Very dark brown.
• Vapor Pressure: 4.73E-08mmHg at 25°C
• Melting Point: 169-170 °C
• Refractive Index: 1.613
• Boiling Point: 443.2 °C at 760 mmHg
• PKA: 11.56±0.10(Predicted)
• Flash Point: 221.8 °C
• PSA: 49.11000
• Density: 1.1 g/cm³
• LogP: 5.31720
• Storage Temp.: Store at 2-8
• Solubility.: dioxane: 50 mg/mL, clear
• Water Solubility.: dioxane: 50 mg/mL, clear
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 300.137496527
• Heavy Atom Count: 23
• Complexity: 386

Purity/Quality:

99% ^*data from raw suppliers

1,3,5-Triphenylformazan ^*data from reagent suppliers

Safty Information:

• Pictogram(s): XnN
• Hazard Codes: Xn,N
• Statements: 22-50/53
• Safety Statements: 60-61-24/25-22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NNC2=CC=CC=C2)N=NC3=CC=CC=C3
• Isomeric SMILES: C1=CC=C(C=C1)/C(=N/NC2=CC=CC=C2)/N=NC3=CC=CC=C3
• Uses: Germination and viability tests. 1,3,5-Triphenyltetrazolium formazan has been used:for the quantification of 2,3,5-triphenyltetrazolium chloride (TTC) reduction activity in bacterial cellsas a standard to study the optical density of formazan produced by TTC-treated milled seedsto stain heart tissue for infarct size assessment or undergo perfusion fixation to allow morphometric studies in addition to histology and immunohistochemistry

Technology Process of Triphenylformazan

There total 47 articles about Triphenylformazan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

triphenyltetrazolium borate → 1,3,5-triphenylformazan (531-52-2)

Guidance literature:

With sodium hydroxide; ascorbic acid; In water;

Reference yield: 86.0%

aniline (62-53-3) + benzaldehyde phenylhydrazone (588-64-7) → 1,3,5-triphenylformazan (531-52-2)

Guidance literature:

aniline; With sodium nitrite; In neat (no solvent); at 20 ℃; Green chemistry;

benzaldehyde phenylhydrazone; With sodium hydroxide; In neat (no solvent); at 20 ℃; pH=10 - 12; Green chemistry;

DOI:10.1246/bcsj.20140298

Reference yield: 82.0%

benzaldehyde (100-52-7) + aniline (62-53-3) + phenylhydrazine (100-63-0) → 1,3,5-triphenylformazan (531-52-2)

Guidance literature:

With water; diethylammonium hydrogen sulphate; sodium nitrite; In neat (no solvent); Microwave irradiation; Green chemistry;

DOI:10.1039/c5ra06363a

upstream raw materials:

benzene diazonium chloride

diethyl ether

1,3-diphenyl-tetraz-1-ene

sodium ethanolate

Downstream raw materials:

triphenyltetrazolium chloride

1,3,5-triphenylverdazyl

(E)-ethyl 4-phenyl-1-(phenyldiazenyl)isoquinoline-3-carboxylate

(E)-dimethyl 1-(phenyldiazenyl)isoquinoline-3,4-dicarboxylate

Refernces

• 1、 Kuhn,R. et al.. "-". . p. 846 - 852. Retrieved 1966.
• 2、 Akhmatova, A. A.,Balandina, A. V.,Chernyaeva, O. Yu.,Kostryukov, S. G.,Kozlov, A. Sh.,Kraynov, E. V.,Lukshina, Yu. I.,Pryanichnikova, M. K.. "Synthesis and Electrochemical Properties of 2-(4-R1-Phenyl)-6-(4-R2-phenyl)-4-phenyl-3,4-dihydro1,2,4,5-tetrazin-1(2H)-yls". . p. 341 - 351. Retrieved 2020/04/27.
• 3、 Ostrovskaya,Shchepilov,Kletter. "Chromogenic Reaction of 1,1-Dimethylhydrazine with Aryltetrazolium Salts". . p. 1385 - 1389. Retrieved 2018/09/11.