Tetrahydropyran-4-methanol

Base Information Edit

Chemical Name:Tetrahydropyran-4-methanol
CAS No.:14774-37-9
Molecular Formula:C6H12O2
Molecular Weight:116.16
Hs Code.:29329990
DSSTox Substance ID:DTXSID90378563
Nikkaji Number:J2.486.867B
Wikidata:Q72480485
Mol file:14774-37-9.mol

Synonyms:14774-37-9;Tetrahydropyran-4-methanol;(tetrahydro-2H-pyran-4-yl)methanol;oxan-4-ylmethanol;(Tetrahydro-pyran-4-yl)-methanol;4-(Hydroxymethyl)tetrahydropyran;tetrahydro-2H-pyran-4-ylmethanol;(Oxan-4-yl)methanol;2H-PYRAN-4-METHANOL, TETRAHYDRO-;tetrahydropyran-4-ylmethanol;MFCD00457804;4-HYDROXYMETHYLTETRAHYDROPYRAN;(tetrahydro-2H-pyran-4-yl) methanol;tetrahydropyran-4-yl-methanol;SCHEMBL104405;(tetrahydropyran-4-yl)methanol;* Tetrahydropyran-4-methanol;Tetrahydro-4H-pyran-4-methanol;DTXSID90378563;YSNVSVCWTBLLRW-UHFFFAOYSA-N;Tetrahydro-2-H-pyran-4-ylmethanol;tetrahydro-2H-pyran-4-yl methanol;tetrahydro-2H-pyran-4-yl-methanol;BCP27520;CS-D1227;Tetrahydro-4-hydroxymethyl-2H-pyran;BBL104396;STK503351;4-(hydroxylmethyl)tetrahydro-2H-pyran;AKOS005146211;PB18487;PS-3348;Tetrahydropyran-4-methanol, AldrichCPR;AC-26737;SY002701;AM20080366;BB 0260255;FT-0648231;T2965;EN300-62680;J-650330;W-205668;F0001-0525;Z979753218

Suppliers and Price of Tetrahydropyran-4-methanol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Hydroxymethyl)tetrahydropyran
10g
$ 385.00

TCI Chemical
Tetrahydropyran-4-methanol >97.0%(GC)
1g
$ 38.00

TCI Chemical
Tetrahydropyran-4-methanol min. 97.0 %
5G
$ 114.00

SynQuest Laboratories
4-(Hydroxymethyl)tetrahydro-2H-pyran 98%
25 g
$ 117.00

SynQuest Laboratories
4-(Hydroxymethyl)tetrahydro-2H-pyran 98%
1 g
$ 16.00

SynQuest Laboratories
4-(Hydroxymethyl)tetrahydro-2H-pyran 98%
5 g
$ 24.00

Oakwood
(Tetrahydro-2H-pyran-4-yl)methanol 95%
5g
$ 25.00

Matrix Scientific
Tetrahydro-2H-pyran-4-ylmethanol 95%
25g
$ 180.00

Matrix Scientific
Tetrahydro-2H-pyran-4-ylmethanol 95%
5g
$ 65.00

J&W Pharmlab
(Tetrahydro-pyran-4-yl)-methanol 97%
5g
$ 25.00

Total 121 raw suppliers

Chemical Property of Tetrahydropyran-4-methanol Edit

Chemical Property:

Vapor Pressure:0.0259mmHg at 25°C
Refractive Index:1.445
Boiling Point:218.9 °C at 760 mmHg
PKA:14.85±0.10(Predicted)
Flash Point:97.7 °C
PSA：29.46000
Density:1 g/cm³
LogP:0.40530
Storage Temp.:Sealed in dry,Room Temperature
Water Solubility.:Slightly soluble in water.
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:116.083729621
Heavy Atom Count:8
Complexity:57.5

Purity/Quality:

99% ^*data from raw suppliers

4-(Hydroxymethyl)tetrahydropyran ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-22-41-37/38
Safety Statements: 26-36/37/39-23-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCC1CO
Uses Used as a reagent in the identification and optimization of pteridinone Toll-like receptor 7 agonists, which can be used for the oral treatment of viral hepatitis. 4-(Hydroxymethyl)tetrahydropyran is also a starting material for [1-[(Tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone which is a drug that acts as CB2 cannabinoid receptor agonist.

Technology Process of Tetrahydropyran-4-methanol

There total 13 articles about Tetrahydropyran-4-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 5337-03-1
tetrahydro-2H-pyran-4-carboxylic acid

: 14774-37-9
(tetrahydro-2H-pyran-4-yl)methanol

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; Heating;
DOI:10.1002/hlca.200390086

Reference yield: 96.0%

: 96835-17-5
ethyl tetrahydro-2H-pyran-4-carboxylate

: 14774-37-9
(tetrahydro-2H-pyran-4-yl)methanol

Guidance literature:: ethyl tetrahydro-2H-pyran-4-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h;

With water; sodium hydroxide; In tetrahydrofuran; ethyl acetate; for 0.5h;