Technology Process of 10-benzyloxycarbonyl-2-(benzyloxycarbonyl)oxy-9,10-dihydroacridine
There total 6 articles about 10-benzyloxycarbonyl-2-(benzyloxycarbonyl)oxy-9,10-dihydroacridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-hydroxy-9,10-dihydroacridine;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 - 5 ℃;
for 1h;
Inert atmosphere;
benzyl chloroformate;
In
tetrahydrofuran; hexane;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1002/adsc.201100563
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: borane-THF / tetrahydrofuran / 1.5 h / Inert atmosphere; Reflux
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 - 5 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
With
n-butyllithium; borane-THF;
In
tetrahydrofuran; hexane;
DOI:10.1002/adsc.201100563
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sulfuric acid / 6 h / 100 °C
2.1: borane-THF / tetrahydrofuran / 1.5 h / Inert atmosphere; Reflux
3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 - 5 °C / Inert atmosphere
3.2: 0 - 20 °C / Inert atmosphere
With
n-butyllithium; borane-THF; sulfuric acid;
In
tetrahydrofuran; hexane;
DOI:10.1002/adsc.201100563