49742-72-5

Basic information

• Product Name: 2-methoxy-10H-acridin-9-one
• Synonyms: 9(10H)-acridinone, 2-methoxy-; TCMDC-123948
• CAS NO: 49742-72-5
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.2426
• Mol File: 49742-72-5.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 406.7°Cat760mmHg
• Flash Point: 199.8°C
• Appearance: /
• Density: 1.233g/cm³
• Vapor Pressure: 7.98E-07mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: 2-methoxy-10H-acridin-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-10H-acridin-9-one(49742-72-5)
• EPA Substance Registry System: 2-methoxy-10H-acridin-9-one(49742-72-5)

Safety Data

• Hazardous Substances Data: 49742-72-5(Hazardous Substances Data)

Usage

General Description

2-Methoxy-10H-acridin-9-one, also known as acridine yellow, is a chemical compound with the molecular formula C14H11NO2. It is a yellow to orange crystalline powder that is insoluble in water and soluble in organic solvents. 2-Methoxy-10H-acridin-9-one has been used as a fluorescent dye, a histological stain, and a pH indicator in laboratory applications. It has also been studied for its potential anti-cancer and anti-microbial properties. As a fluorescent dye, it is used in biological and medical research to stain DNA and RNA in cells and tissues, and as a pH indicator, it changes color from red to yellow at pH 4.4-6.0. Additionally, it has been investigated for its potential use in the development of new materials and technologies. Overall, 2-Methoxy-10H-acridin-9-one has a range of diverse applications in various scientific and industrial fields.

InChI:InChI=1/C14H11NO2/c1-17-9-6-7-13-11(8-9)14(16)10-4-2-3-5-12(10)15-13/h2-8H,1H3,(H,15,16)

Upstream product

• 7466-73-1 2-hydroxy-9-acridanone 
• 77-78-1 dimethyl sulfate 
• 57659-40-2 N-(4-methoxy-phenyl)-anthraniloyl chloride 
• 89224-95-3 5-methoxy-2-(phenylamino)benzoic acid 
• 13501-67-2 N-(p-methoxyphenyl)anthranilic acid 
• 104-94-9 4-methoxy-aniline 
• 118-91-2 ortho-chlorobenzoic acid 
• 62-53-3 aniline 
• 91-40-7 2-(phenylamino)benzoic acid 
• 61556-11-4 9-acridone-2-sulfonic acid 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 118-92-3 anthranilic acid 
• 23592-51-0 1-<2-<(4-Methoxyphenyl)amino>phenyl>ethanon 
• 1080675-00-8 1-((5-methoxy-2-(phenylamino))phenyl)ethanone 

Downstream Products

• 77213-46-8 10-benzyl-2-methoxyacridin-9(10H)-one 
• 83707-27-1 Methoxy-2, O-benzyl acridine 
• 77213-60-6 benzoate-9 de methoxy-2 acridine 
• 77213-51-5 10-(4-Chloro-benzyl)-2-methoxy-10H-acridin-9-one 
• 77213-49-1 10-(2-Chloro-benzyl)-2-methoxy-10H-acridin-9-one 
• 77213-52-6 2-methoxy-10-(4-methylbenzyl)acridin-9(10H)-one 
• 77213-55-9 2-methoxy-10-dimethylaminopropyl-9-acridinone 
• 77213-48-0 10-(4-Bromo-benzyl)-2-methoxy-10H-acridin-9-one 
• 77213-47-9 2-Methoxy-10-(2-methyl-benzyl)-10H-acridin-9-one 
• 77213-50-4 10-(3-Chloro-benzyl)-2-methoxy-10H-acridin-9-one 
• 7466-73-1 2-hydroxy-9-acridanone 
• 130505-87-2 10-Benzyl-2-methoxy-10H-acridine-9-thione 
• 130505-90-7 10-Benzyl-2-ethylsulfanyl-10H-acridine-9-thione 
• 3295-60-1 2-methoxyacridine 

Relevant articles and documents

Acid-catalyzed oxidative cross-coupling of acridans with silyl diazoenolates and a Rh-catalyzed rearrangement: two-step synthesis of γ-(9-acridanylidene)-β-keto esters

A MsOH-catalyzed oxidative cross-coupling of acridans and silyl diazoenolates and a Rh2(OAc)4-catalyzed rearrangement of the resultant diazo products are described. The reactions provide various γ-(9-acridanylidene)-β-keto esters in good yields, which bear an active α-methylene unit for further functionalization.

Acridone derivative containing amino sugar structure, and preparation method and application thereof (by machine translation)

The invention belongs to, the technical field of pharmaceutical chemistry, and particularly relates, to a preparation method of an acridone derivative containing an. amino sugar structure and a preparation method of the acridone derivative containing an a

Dimethyl sulfoxide-aided copper(0)-catalyzed intramolecular decarbonylative rearrangement of N-aryl isatins leading to acridones

Described here is the first example of Cu(0)-catalyzed intramolecular decarbonylative rearrangements of readily available N-aryl isatins assisted by solvent dimethyl sulfoxide (DMSO) under air atmosphere and additive-free conditions leading to various biologically important acridones in good to excellent yields. This novel transformation is proposed to go through a sequential DMSO-aided Cu insertion into the amide C–N bond, CO extrusion, Cu migration, reductive elimination and DMSO-aided proton migration processes, involving multiple types of bond cleavage and formation in a single chemical step.