3295-60-1

Basic information

• Product Name: 2-Methoxyacridine
• Synonyms: 2-Methoxyacridine
• CAS NO: 3295-60-1
• Molecular Formula: C₁₄H₁₁NO
• Molecular Weight: 209.2432
• Mol File: 3295-60-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 384.2°Cat760mmHg
• Flash Point: 139.7°C
• Appearance: /
• Density: 1.196g/cm³
• Vapor Pressure: 9.19E-06mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: 2-Methoxyacridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methoxyacridine(3295-60-1)
• EPA Substance Registry System: 2-Methoxyacridine(3295-60-1)

Safety Data

• Hazardous Substances Data: 3295-60-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H11NO/c1-16-12-6-7-14-11(9-12)8-10-4-2-3-5-13(10)15-14/h2-9H,1H3

Upstream product

• 26706-96-7 7-methoxy-1,2,3,4-tetrahydroacridine 
• 86-38-4 6,9-dichloro-2-methoxyacridine 
• 118-91-2 ortho-chlorobenzoic acid 
• 112934-63-1 1-(4Methoxyphenyl)-1H-indole-2,3-dione 
• 42501-87-1 1-(2-fluorophenyl)-N-(4-methoxyphenyl)methanimine 
• 1512859-13-0 C₂₁H₂₀N₂O₂ 
• 104-94-9 4-methoxy-aniline 
• 696-62-8 para-iodoanisole 
• 529-23-7 o-aminobenzaldehyde 
• 108694-49-1 4'-methoxydiphenylamine-2-carboxaldehyde 
• 1330681-27-0 (4-methoxyphenyl)(mesityl)iodonium trifluoromethanesulfonate 
• 271-58-9 anthranil 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 88-65-3 2-bromobenzoic-acid 

Downstream Products

• 77282-37-2 bromo-3 methoxy-2 acridinedione-1,4 
• 22817-17-0 acridin-2-ol 

Relevant articles and documents

Cu-catalyzed cascade reaction of isoxazoles with diaryliodonium salts for the synthesis of acridines

A straightforward and efficient synthesis of acridine derivatives via a copper-catalyzed cascade reaction among isoxazoles and diaryliodonium salts is achieved. Various mono-, multi-substituted and 9-substituted acridine derivatives could be obtained in moderate to good yields. The process has gone through tandem double arylation and Friedel-Crafts reactions.

Amine compound for inhibiting SSASASASASASASAO/VAP-1 and application thereof in medicine (by machine translation)

The invention relates to an amine compound serving as an amino urea-sensitive amine oxidase (SSASAO) and/or a vascular adhesion protein -1 (VAP AP AP-1) inhibitor and application thereof in medicine, and further relates to a pharmaceutical composition containing the compound. The compounds or pharmaceutical compositions described herein may be used to treat inflammation and/or inflammation related diseases, diabetes and/or diabetes-related diseases, psychiatric disorders, ischemic diseases, vascular diseases, fibrosis or tissue transplant rejection. (by machine translation)

Facile synthesis of acridines via Pd(0)-diphosphine complex-catalyzed tandem coupling/cyclization protocol

A facile and efficient approach for the synthesis of a variety of acridines via the tandem coupling/cyclization of substituted 2-bromobenzaldehydes and anilines is described. The reaction can be accomplished with ease in the presence of a catalytic amount of Pd2(dba)3 and diphosphine ligand dppf, providing a broad range of substituted acridines in good to excellent yields (up to 99%). The Lewis acid, AlCl3, is required to promote the cyclization for less electron-rich anilines.