1,4-Dibromo-2,5-dimethylbenzene

Base Information

• Chemical Name: 1,4-Dibromo-2,5-dimethylbenzene
• CAS No.: 1074-24-4
• Molecular Formula: C8H8Br2
• Molecular Weight: 263.96
• Hs Code.: 29039990
• European Community (EC) Number: 214-038-2
• NSC Number: 106321
• DSSTox Substance ID: DTXSID9061467
• Nikkaji Number: J80.145C
• Wikidata: Q72464208
• Mol file: 1074-24-4.mol

Synonyms:1,4-Dibromo-2,5-dimethylbenzene;1074-24-4;2,5-Dibromo-p-xylene;Benzene, 1,4-dibromo-2,5-dimethyl-;p-Xylene, 2,5-dibromo-;2,5-Dibromo-1,4-dimethylbenzene;2,5-Dimethyl-1,4-dibromobenzene;EINECS 214-038-2;NSC 106321;2,5-DIBROMO-4-XYLENE;2,4-dibromobenzene;MFCD00000091;NSC106321;p-Xylene,5-dibromo-;SCHEMBL120851;DTXSID9061467;Benzene,4-dibromo-2,5-dimethyl-;1,4,-Dibromo-2,5-dimethylbenzene;1,4-dibromo-2,5-Dimethyl benzene;TD1272;AKOS003617654;AM62576;CS-W007702;NSC-106321;1,4-Dibromo-2,5-dimethylbenzene, 98%;AC-19502;BP-21221;D1841;FT-0610282;EN300-154442;A801693;AH-034/04858064;J-802055;W-108747

Chemical Property of 1,4-Dibromo-2,5-dimethylbenzene

Chemical Property:

• Appearance/Colour: white to slightly yellow shiny crystalline powder
• Vapor Pressure: 0.0195mmHg at 25°C
• Melting Point: 72-74 °C(lit.)
• Refractive Index: 1.543-1.545
• Boiling Point: 260.8 °C at 760 mmHg
• Flash Point: 124.2 °C
• PSA: 0.00000
• Density: 1.71 g/cm³
• LogP: 3.82840
• Storage Temp.: Room temperature.
• Water Solubility.: Soluble in toluene, hot ethanol and hot methanol.Insoluble in water.
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 263.89723
• Heavy Atom Count: 10
• Complexity: 99.8

Purity/Quality:

99% ^*data from raw suppliers

1,4-Dibromo-2,5-dimethylbenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38-51/53
• Safety Statements: 26-37/39-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1Br)C)Br
• Uses: 1,4-dibromo-2,5-dimethylbenzene has been used in the preparation of 4,4″-diformyl-2′,5′-dimethyl-1,1′.4′,1″-terphenyl. It has also been used in the preparation of 1,4-diformyl-2,5-dimethylbenzene.

Technology Process of 1,4-Dibromo-2,5-dimethylbenzene

There total 13 articles about 1,4-Dibromo-2,5-dimethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

para-xylene (106-42-3) → 2,5-dibromo-p-xylene (1074-24-4) + 2,3,5,6-tetrabromo-p-xylene (23488-38-2) + 2,3,5-tribromo-p-xylene (117572-80-2)

Guidance literature:

With bromine; Nitrogen dioxide; In water; trifluoroacetic acid; at 20 ℃; for 0.1h; Product distribution; other time;

Reference yield: 96.5%

para-xylene (106-42-3) → 2,5-dibromo-p-xylene (1074-24-4)

Guidance literature:

With bromine; iodine; In dichloromethane; water; at 12 ℃; for 18h;

Reference yield: 92.0%

para-xylene (106-42-3) → 4-bromo-m-xylene (553-94-6) + 2,5-dibromo-p-xylene (1074-24-4)

Guidance literature:

With carbon dioxide; bromine; at 40 ℃; for 2h; under 187519 Torr; Supercritical conditions; Green chemistry;

DOI:10.1039/c4ra10557e

upstream raw materials:

para-xylene

4-bromo-2,5-dimethylaniline

2,5-dimethylbenzenesulfonic acid

iodine

Downstream raw materials:

1,4-dibromo-2,5-bis-diacetoxymethyl-benzene

1,2,4,5-tetramethylbenzene

C₆₆H₅₀O₂

1,4-Bis(2,2-dimethoxyethylthio)-2,5-dimethylbenzene

Refernces

• 1、 He, Ying,Cheng, Nianhe,Xu, Xin,Fu, Jiawei,Wang, Jun-an. "A high efficiency pure organic room temperature phosphorescence polymer PPV derivative for OLED". . p. 247 - 251. Retrieved 2019.
• 2、 Cai, Zhi-Bin,Dai, Huan,Li, Sheng-Li,Lou, Qiao-Xian,Tian, Yu-Peng. "Rational design, facile synthesis, and linear/nonlinear optical properties of novel two-photon absorption stilbene derivatives with different configurations". . . Retrieved 2021.
• 3、 Yang, Junjuan,Wu, Yuanyuan,Wu, Xiaowei,Liu, Wenjing,Wang, Yaofang,Wang, Junwen. "An N-heterocyclic carbene-functionalised covalent organic framework with atomically dispersed palladium for coupling reactions under mild conditions". . p. 5267 - 5273. Retrieved 2019.
• 4、 Huang, Chibao,Yang, Yuzhu,Li, Youfeng,Lv, Guoling. "A two-photon fluorescent lipid raft probe derived from dicyanostilbene and similar to cholesterol’s structure". . p. 1223 - 1230. Retrieved 2021.
• 5、 Tang, Niu,Song, Xingxing,Yang, Tianbao,Qiu, Renhua,Yin, Shuang-Feng. "Synthesis and structure of the bimetallic organoantimony catalyst and its application in diastereoselective direct Mannich reaction as facile separation catalytic system". . . Retrieved 2021/04/27.