N-tosyl-2,5-dimethylpyrrole

Base Information

• Chemical Name: N-tosyl-2,5-dimethylpyrrole
• CAS No.: 1166995-00-1
• Molecular Formula: C₁₃H₁₅NO₂S
• Molecular Weight: 249.334
• Mol file: 1166995-00-1.mol

Synonyms:N-tosyl-2,5-dimethylpyrrole

Chemical Property of N-tosyl-2,5-dimethylpyrrole

Chemical Property:

Purity/Quality:

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Technology Process of N-tosyl-2,5-dimethylpyrrole

There total 1 articles about N-tosyl-2,5-dimethylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2,2,5,5-tetraethoxyhexane (82063-95-4) + toluene-4-sulfonamide (70-55-3) → N-tosyl-2,5-dimethylpyrrole (1166995-00-1)

Guidance literature:

With phosphorus pentoxide; In toluene; at 20 - 110 ℃; Inert atmosphere;

DOI:10.1055/s-0028-1088005

Reference yield: 34.0%

N-tosyl-2,5-dimethylpyrrole (1166995-00-1) + diphenylmethyl phenyl sulfone (5433-76-1) → 1-tosyl-3-benzhydryl-2,5-dimethylpyrrole

Guidance literature:

With scandium tris(trifluoromethanesulfonate); In 1,2-dichloro-ethane; at 80 ℃; for 12h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.6b00744

Reference yield: 27.0%

N-tosyl-2,5-dimethylpyrrole (1166995-00-1) → N-tosyl-2,5-diformylpyrrole (1166995-02-3)

Guidance literature:

With ammonium cerium (IV) nitrate; In water; acetonitrile; for 3h; Reflux;

DOI:10.1055/s-0028-1088005

upstream raw materials:

2,2,5,5-tetraethoxyhexane

toluene-4-sulfonamide

Downstream raw materials:

N-tosyl-2,5-diformylpyrrole

Refernces