4-tert-butyl-1-methylcyclohexyl bromide

Base Information

• Chemical Name: 4-tert-butyl-1-methylcyclohexyl bromide
• CAS No.: 910620-53-0
• Molecular Formula: C₁₁H₂₁Br
• Molecular Weight: 233.192
• Mol file: 910620-53-0.mol

Synonyms:4-tert-butyl-1-methylcyclohexyl bromide

Chemical Property of 4-tert-butyl-1-methylcyclohexyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-tert-butyl-1-methylcyclohexyl bromide

There total 2 articles about 4-tert-butyl-1-methylcyclohexyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-tert-butyl-1-methylcyclohexanol (6353-54-4) → 4-tert-butyl-1-methylcyclohexyl bromide (910620-53-0)

Guidance literature:

With phosphorus tribromide; In diethyl ether; at -10 ℃;

DOI:10.1002/chem.200400545

Reference yield:

→ 4-tert-butyl-1-methylcyclohexyl bromide (910620-53-0)

Guidance literature:

DOI:10.1021/ja00754a035 DOI:10.1039/j39700000182 DOI:10.1021/ja00754a035

Reference yield: 83.0%

2-phenyl-1,2,3,4-tetrahydroisoquinoline (3340-78-1) + 4-tert-butyl-1-methylcyclohexyl bromide (910620-53-0) → 1-(2-methylcyclohexan-2-yl)-2-phenyl-1,2,3,4-tetrahydroisoquinoline

Guidance literature:

With 2,4,6-trimethyl-pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 20 ℃; for 16h; Inert atmosphere; Schlenk technique; Irradiation;

DOI:10.1002/anie.201704513

upstream raw materials:

4-tert-butyl-1-methylcyclohexanol

Downstream raw materials:

trans-3-(4'-tert-butyl-1'-methylcyclohexyl)butyronitrile

cis-3-(4'-tert-butyl-1'-methylcyclohexyl)butyronitrile

1-(tert-butyl)-4-methylcyclohexane

trans-2-(4'-tert-butyl-1'-methylcyclohexyl)butyrodinitrile

Refernces