Oxamic hydrazide

Base Information

• Chemical Name: Oxamic hydrazide
• CAS No.: 515-96-8
• Molecular Formula: C2H5 N3 O2
• Molecular Weight: 103.081
• Hs Code.: 29280000
• European Community (EC) Number: 208-213-2
• NSC Number: 45889
• UNII: BET2UBD6NV
• DSSTox Substance ID: DTXSID00199483
• Nikkaji Number: J6.301K
• Wikidata: Q27274619
• Mol file: 515-96-8.mol

Synonyms:oxamic acid hydrazide

Chemical Property of Oxamic hydrazide

Chemical Property:

• Appearance/Colour: white powder
• Melting Point: 216-218 °C (dec.)(lit.)
• Refractive Index: 1.524
• Boiling Point: °Cat760mmHg
• PKA: 10.72±0.20(Predicted)
• Flash Point: °C
• PSA: 98.21000
• Density: 1.432g/cm³
• LogP: -0.74690
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 103.038176411
• Heavy Atom Count: 7
• Complexity: 99.1

Purity/Quality:

98% ^*data from raw suppliers

2-Hydrazinyl-2-oxoacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 36/37/39-45-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)(C(=O)NN)N
• Uses: As a reagent for aldehydes and ketones.

Technology Process of Oxamic hydrazide

There total 7 articles about Oxamic hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

1,2-dimethoxyethane (110-71-4) + N-[2-(3-cyclopentyloxy-4-methoxyphenyl)ethyl]oxamic acid (141332-77-6) → N'-Amino-N-[2-(3-cyclopentyloxy-4-methoxyphenyl)ethyl]oxamide (141332-90-3) + oxalamic acid hydrazide (515-96-8)

Guidance literature:

With hydrazine;

Reference yield:

Ethyl oxamate (617-36-7) → oxalamic acid hydrazide (515-96-8)

Guidance literature:

With hydrazine; In ethanol; for 3h; Heating;

DOI:10.1016/0223-5234(90)90168-3

Reference yield:

methyl hydrazino(oxo)acetate (63970-76-3) → oxalamic acid hydrazide (515-96-8)

Guidance literature:

With ammonia; water;

upstream raw materials:

methyl hydrazino(oxo)acetate

Ethyl oxamate

hydrogenchloride

ammonia

Downstream raw materials:

5-nitro-furfural-aminooxalylhydrazone

oxalamic acid-(1-phenyl-ethylidenehydrazide)

N'-aminooxalyl-O⁶-benzoyl-2,5-anhydro-allonohydrazonic(or altronohydrazonic) acid amide

5-(O⁵-benzoyl-ξ-D-ribofuranosyl)-1H-[1,2,4]triazole-3-carboxylic acid hydrazide

Refernces

• 1、 Cave,Galons,Miocque,Rinjard,Tran,Binet. "Antihypertensive actions of hydrazidones: Study of acylated dichloroarylhydrazones". . p. 75 - 79. Retrieved 2007/10/02.