(R)-(6-Methoxyquinolin-4-yl)((1R,2R,4R,5S)-5-vinylquinuclidin-2-yl)methanol

Base Information

• Chemical Name: (R)-(6-Methoxyquinolin-4-yl)((1R,2R,4R,5S)-5-vinylquinuclidin-2-yl)methanol
• CAS No.: 50-54-4
• Molecular Formula: 2C₂₀H₂₄N₂O₂*H₂O₄S
• Molecular Weight: 746.925
• NCI Thesaurus Code: C48014
• RXCUI: 9069
• ChEMBL ID: CHEMBL1741006
• Mol file: 50-54-4.mol

Synonyms:Adaquin;Apo Quinidine;Apo-Quinidine;Chinidin;Quincardine;Quinidex;Quinidine;Quinidine Sulfate;Quinora;Sulfate, Quinidine

Chemical Property of (R)-(6-Methoxyquinolin-4-yl)((1R,2R,4R,5S)-5-vinylquinuclidin-2-yl)methanol

Chemical Property:

• Vapor Pressure: 1.13E-17mmHg at 25°C
• Melting Point: 212°C
• Boiling Point: 495.9°Cat760mmHg
• Flash Point: 253.7°C
• PSA: 174.16000
• Density: g/cm³
• LogP: 6.65020
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 324.183778013
• Heavy Atom Count: 24
• Complexity: 457

Purity/Quality:

99.9% ^*data from raw suppliers

Quinidinesulphate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 22-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O
• Isomeric SMILES: COC1=CC2=C(C=CN=C2C=C1)[C@H]([C@H]3C[C@H]4CCN3C[C@H]4C=C)O
• Recent ClinicalTrials: Study of the Electrocardiographic Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects
• Recent NIPH Clinical Trials: Quinidine sulfate administration for intractable epilepsy with KCNT1 gene mutation
• Uses: Cardiac depressant (anti-arrhythmic).