1,5-DIAMINOPENTANE DIHYDROCHLORIDE

Base Information

• Chemical Name: 1,5-DIAMINOPENTANE DIHYDROCHLORIDE
• CAS No.: 1476-39-7
• Molecular Formula: C5H14 N2 . 2 Cl H
• Molecular Weight: 175.101
• Hs Code.: 29212900
• NSC Number: 5862
• Mol file: 1476-39-7.mol

Synonyms:1,5-Pentanediamine,dihydrochloride (8CI,9CI); 1,5-Diaminopentane dihydrochloride;1,5-Pentanediammonium dichloride; Cadaverine dihydrochloride; Cadaverinehydrochloride; Cadaverinium dichloride; Pentamethylenediamine dihydrochloride

Chemical Property of 1,5-DIAMINOPENTANE DIHYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.961mmHg at 25°C
• Melting Point: 260-262 °C(lit.)
• Boiling Point: 179°C at 760 mmHg
• Flash Point: 76.5°C
• PSA: 52.04000
• Density: 1.03 g/mL at 20 °C
• LogP: 3.07870
• Storage Temp.: 2-8°C
• Water Solubility.: almost transparency
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 138.0923762
• Heavy Atom Count: 8
• Complexity: 25.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,5-Diaminopentane Dihydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCN)CCN.Cl
• Uses: Cadaverine dihydrochloride may be used in the cadaverine tolerance test to evaluate the tolerance of Escherichia coli K12 wild-type strain W3110 for cadaverine in chemically defined R/2 medium. It may be used for the crystallization of maltose-binding protein (MBP)-parathyroid hormone receptor (PTH1R) extracellular domain (ECD)-His6 fusion protein. It has been used as standard compound for the chromatographic quantification of biogenic amines in fish tissue samples.

Technology Process of 1,5-DIAMINOPENTANE DIHYDROCHLORIDE

There total 14 articles about 1,5-DIAMINOPENTANE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N,N,N',N'-Tetrakis(trimethylsilyl)-1,5-pentandiamin (65898-76-2) → Hexamethyldisiloxane (107-46-0) + 1,5-diaminopentane dihydrochloride (1476-39-7)

Guidance literature:

With hydrogenchloride;

Reference yield: 93.0%

L-lysine (56-87-1,3506-25-0) → 1,5-diaminopentane dihydrochloride (1476-39-7)

Guidance literature:

L-lysine; With (R)-Carvone; In propan-1-ol; at 190 ℃; for 0.283333h; under 11251.1 Torr; Sealed tube;

With hydrogenchloride; In propan-1-ol; water; at 190 ℃; for 0.0833333h;

Reference yield: 93.0%

C25H38N2 → 1,5-diaminopentane dihydrochloride (1476-39-7)

Guidance literature:

With hydrogenchloride; In propan-1-ol; at 190 ℃; for 0.283333h; Temperature; Green chemistry;

DOI:10.1080/00397911.2015.1100745

upstream raw materials:

1,5-diaminopentane

N,N,N',N'-Tetrakis(trimethylsilyl)-1,5-pentandiamin

1,5-dibromo-pentane

1,5-diazidopentane

Downstream raw materials:

5-tert-butoxycarbonylamino-1-aminopentane

N,N'-Didansyl-cadaverin

2,3,4,5-tetrahydropyridine

N,N'-pentane-1,5-diylbis(4-cyanobenzamide)

Refernces

• 1、 Pospieszna-Markiewicz, Izabela,Radecka-Paryzek, Wanda,Kubicki, Maciej. "Cadaverinium dichloride: A case of centro-non-centrosymmetric ambiguity". . p. o399-o401. Retrieved 2006.
• 2、 -. "Method for production of 1,5-pentanediamine by chemical decarboxylation of L-lysine and separation and extraction method". Paragraph 0029-0047. . Retrieved 2019/08/30.