cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester

Base Information

• Chemical Name: cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester
• CAS No.: 735331-42-7
• Molecular Formula: C₂₀H₁₀F₁₀O₄
• Molecular Weight: 504.281
• Mol file: 735331-42-7.mol

Synonyms:cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester

Chemical Property of cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester

There total 2 articles about cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclohexane-1,4-dicarboxylic acid (619-81-8,619-82-9,1076-97-7) + pentafluorophenyl trifloroacetate (14533-84-7) → cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester (735331-42-7)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1021/jm010375a

Reference yield:

2,3,4,5,6-pentafluorophenol (771-61-9) + trans-hexahydroterephthalic acid (619-82-9) → cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester (735331-42-7)

Guidance literature:

With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 0 ℃; for 2h;

Reference yield:

cyclohexane-1,4-dicarboxylic acid dipentafluorophenylester (735331-42-7) + 4-amino-1-(3-methyl-butyl)-1H-pyrrole-2-carboxylic acid (2-carbamimidoyl-ethyl)-amide (404336-17-0) → cyclohexane-1,4-dicarboxylic acid bis-{[5-(2-carbamimidoyl-ethylcarbamoyl)-1-(3-methyl-butyl)-1H-pyrrol-3-yl]-amide}

Guidance literature:

In N,N-dimethyl-formamide; at 55 ℃; for 15h;

DOI:10.1021/jm010375a

upstream raw materials:

2,3,4,5,6-pentafluorophenol

trans-hexahydroterephthalic acid

cyclohexane-1,4-dicarboxylic acid

pentafluorophenyl trifloroacetate

Refernces

• 1、 Mezo,Seprodi,Erchegyi,et al.. "Design and synthesis of inhibitory analogues of LH-RH with increased antiovulatory potency". . p. 173 - 187. Retrieved 2007/10/02.