Phosphohydroxypyruvic acid

Base Information

• Chemical Name: Phosphohydroxypyruvic acid
• CAS No.: 3913-50-6
• Molecular Formula: C3H5O7P
• Molecular Weight: 184.042
• Hs Code.: 2931900090
• UNII: ZX4PWG857L
• DSSTox Substance ID: DTXSID70959935
• Nikkaji Number: J2.180.747H
• Wikipedia: Phosphohydroxypyruvic_acid
• Wikidata: Q4353545
• Metabolomics Workbench ID: 37557
• Mol file: 3913-50-6.mol

Synonyms:3-phosphohydroxypyruvate;phosphohydroxypyruvic acid

Chemical Property of Phosphohydroxypyruvic acid

Chemical Property:

• Vapor Pressure: 5.37E-12mmHg at 25°C
• Boiling Point: 497.8°C at 760 mmHg
• Flash Point: 254.9°C
• PSA: 210.39000
• Density: 1.930
• LogP: 5.10370
• Storage Temp.: −20°C
• XLogP3: -2.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 183.97728949
• Heavy Atom Count: 11
• Complexity: 214

Purity/Quality:

98%Min ^*data from raw suppliers

Hydroxypyruvic acid phosphate lithium salt ≥95% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 21/22
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(=O)C(=O)O)OP(=O)(O)O
• Uses: 3-Hydroxy-2,2-dimethoxy-propanoic Acid-3-phosphatetri(cyclohexylammonium) Salt is used in the preparation of mTORC1 signaling agents that activates ATF.

Technology Process of Phosphohydroxypyruvic acid

There total 1 articles about Phosphohydroxypyruvic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-(-)-3-phosphoglyceric acid (820-11-1,3443-58-1,73358-94-8,111614-09-6) → hydroxypyruvic acid phosphate (3913-50-6)

Guidance literature:

With Entamoeba histolytica D-phosphoglycerate dehydrogenase; 2-(cyclohexylamino)ethanesulfonic acid; NAD; 1,4-dithiothreitol; In water; at 20 ℃; for 0.05h; pH=9.0 - 9.5; Reagent/catalyst; Catalytic behavior; Kinetics;

DOI:10.1111/febs.13091

Reference yield:

hydroxypyruvic acid phosphate (3913-50-6) → L-phosphoserine (407-41-0,7331-08-0)

Guidance literature:

With α-ketoglutaric acid; L-glutamic acid; phosphoserine aminotransferasev; Enzymatic reaction;

DOI:10.1021/acs.biochem.9b00579

upstream raw materials:

D-(-)-3-phosphoglyceric acid

Downstream raw materials:

L-phosphoserine

Refernces