Technology Process of 2-cyano-2-diazo-N-(4-methoxyphenethyl)-N-methylacetamide
There total 5 articles about 2-cyano-2-diazo-N-(4-methoxyphenethyl)-N-methylacetamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,4,6-trimethyl-pyridine; imidazole-1-sulfonyl azide hydrochloride;
In
acetonitrile;
at 55 ℃;
for 18h;
Sealed tube;
DOI:10.1021/ja401610p
- Guidance literature:
-
Multi-step reaction with 4 steps
1: toluene; water / 0.5 h / 0 - 22 °C / Inert atmosphere
2: borane-THF / tetrahydrofuran / 4 h / Inert atmosphere; Reflux
3: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / Inert atmosphere
4: imidazole-1-sulfonyl azide hydrochloride; 2,4,6-trimethyl-pyridine / acetonitrile / 18 h / 55 °C / Sealed tube
With
2,4,6-trimethyl-pyridine; imidazole-1-sulfonyl azide hydrochloride; borane-THF; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran; water; toluene; acetonitrile;
DOI:10.1021/ja401610p
- Guidance literature:
-
Multi-step reaction with 3 steps
1: borane-THF / tetrahydrofuran / 4 h / Inert atmosphere; Reflux
2: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / Inert atmosphere
3: imidazole-1-sulfonyl azide hydrochloride; 2,4,6-trimethyl-pyridine / acetonitrile / 18 h / 55 °C / Sealed tube
With
2,4,6-trimethyl-pyridine; imidazole-1-sulfonyl azide hydrochloride; borane-THF; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran; acetonitrile;
DOI:10.1021/ja401610p
