2-Amino-2-thiazoline hydrochloride

Base Information

• Chemical Name: 2-Amino-2-thiazoline hydrochloride
• CAS No.: 3882-98-2
• Molecular Formula: C3H6N2S . ClH
• Molecular Weight: 138.621
• Hs Code.: 2934100090
• European Community (EC) Number: 223-416-6
• UNII: BR3X7522FX
• Wikidata: Q27274830
• Mol file: 3882-98-2.mol

Synonyms:2-amino-2-thiazoline;2-Amino-4-thiazoline;2-aminothiazoline;2-aminothiazoline monohydrobromide;2-aminothiazoline nitrate;2-aminothiazoline phosphate;2-aminothiazoline sulfate;Revercan

Chemical Property of 2-Amino-2-thiazoline hydrochloride

Chemical Property:

• Appearance/Colour: Cream colored crystalline solid
• Vapor Pressure: 0.105mmHg at 25°C
• Melting Point: 200-202 °C(lit.)
• Boiling Point: 269.9 °C at 760 mmHg
• Flash Point: 117.1 °C
• PSA: 63.68000
• LogP: 0.98580
• Water Solubility.: >=10 g/100 mL at 24 ºC
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 138.0018471
• Heavy Atom Count: 7
• Complexity: 78.9

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-2-thiazoline hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CSC(=N1)N.Cl

Technology Process of 2-Amino-2-thiazoline hydrochloride

There total 1 articles about 2-Amino-2-thiazoline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloroethanamine hydrochloride (870-24-6) + thiourea (17356-08-0) → 2-amino-4,5-dihydrothiazole hydrochloride (3882-98-2)

Guidance literature:

In water; for 12h;

Reference yield: 88.0%

2-amino-4,5-dihydrothiazole hydrochloride (3882-98-2) + terephthaloyl chloride (100-20-9) → N,N'-bis(2-thiazolinyl)terephthalamide

Guidance literature:

With triethylamine; In chloroform; at 20 ℃;

DOI:10.1081/SCC-200028517

Reference yield: 87.54%

2-amino-4,5-dihydrothiazole hydrochloride (3882-98-2) + (1,2-dibromoethyl)benzene (102921-26-6,93-52-7) → Tetramisole (5036-02-2)

Guidance literature:

2-amino-4,5-dihydrothiazole hydrochloride; (1,2-dibromoethyl)benzene; With sodium carbonate; In N,N-dimethyl-formamide; at 85 ℃; for 2h;

In N,N-dimethyl-formamide; at 160 ℃; for 16h; Temperature; Reagent/catalyst;

upstream raw materials:

2-chloroethanamine hydrochloride

thiourea

Downstream raw materials:

7-phenyl-2,3-dihydro-thiazolo[3,2-a]pyrimidin-5-one

6-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-one

6-phenyl-2,3-dihydro-thiazolo[3,2-a]pyrimidin-7-one

2-Chloro-N-(4,5-dihydro-thiazol-2-yl)-2-phenyl-acetamide

Refernces