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2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine

Base Information Edit
  • Chemical Name:2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine
  • CAS No.:161696-76-0
  • Molecular Formula:C16H18 N4 S
  • Molecular Weight:298.412
  • Hs Code.:2934999090
  • Mol file:161696-76-0.mol
2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine

Synonyms:4'-Desmethylolanzapine;Desmethylolanzapine; LY 170055; N-Demethylolanzapine

Suppliers and Price of 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • N-DemethylOlanzapine
  • 100mg
  • $ 910.00
  • Sigma-Aldrich
  • Desmethylolanzapine dihydrochloride solution 1.0?mg/mL in acetonitrile: water (1:1) (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • 1 mL
  • $ 173.00
  • Sigma-Aldrich
  • Desmethylolanzapine dihydrochloride solution 1.0 mg/mL in acetonitrile: water (1:1) (as free base), ampule of 1 mL, certified reference material
  • 069-1ml
  • $ 168.00
  • Medical Isotopes, Inc.
  • N-Desmethylolanzapinehydrate
  • 10 mg
  • $ 1790.00
  • Crysdot
  • 2-Methyl-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine 95+%
  • 25mg
  • $ 200.00
  • Crysdot
  • 2-Methyl-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine 95+%
  • 100mg
  • $ 640.00
  • Biosynth Carbosynth
  • N-Demethyl olanzapine
  • 100 mg
  • $ 640.00
  • Biosynth Carbosynth
  • N-Demethyl olanzapine
  • 50 mg
  • $ 350.00
  • Biosynth Carbosynth
  • N-Demethyl olanzapine
  • 25 mg
  • $ 200.00
  • Biosynth Carbosynth
  • N-Demethyl olanzapine
  • 10 mg
  • $ 100.00
Total 32 raw suppliers
Chemical Property of 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine Edit
Chemical Property:
  • Vapor Pressure:1.02E-09mmHg at 25°C 
  • Melting Point:144.5°C 
  • Boiling Point:489.2°C at 760 mmHg 
  • PKA:8.58±0.10(Predicted) 
  • Flash Point:249.7°C 
  • PSA:67.90000 
  • Density:1.38g/cm3 
  • LogP:2.93730 
  • Storage Temp.:-20°C Freezer 
Purity/Quality:

98%,99%, *data from raw suppliers

N-DemethylOlanzapine *data from reagent suppliers

Safty Information:
  • Pictogram(s): F,Xn 
  • Hazard Codes:F,Xn 
  • Statements: 11-20/21/22-36 
  • Safety Statements: 16-26-36/37 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses A metabolite of Olanzapine A metabolite of Olanzapine.
Technology Process of 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine

There total 9 articles about 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
In butan-1-ol; for 8h; Product distribution / selectivity; Heating / reflux;
Guidance literature:
With potassium hydroxide; In ethanol; for 28h; Reflux;
DOI:10.1016/j.bmcl.2013.02.045
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