Technology Process of C13H11ClN2O
There total 5 articles about C13H11ClN2O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
In
dichloromethane;
at 20 ℃;
for 0.166667h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: n-butyllithium; N,N,N',N'',N'''-pentamethyldiethylenetriamine / tetrahydrofuran / 2 h / -78 °C
1.2: -78 °C
2.1: sulfuric acid / 12 h / Heating / reflux
3.1: iron(III)-acetylacetonate / 1-methyl-pyrrolidin-2-one / 1 h / 0 °C
4.1: lithium hydroxide; water / methanol; water / 1 h
5.1: N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane / 0.17 h / 20 °C
With
lithium hydroxide; n-butyllithium; N,N,N',N'',N'''-pentamethyldiethylenetriamine; water; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
iron(III)-acetylacetonate; sulfuric acid;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; methanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iron(III)-acetylacetonate / 1-methyl-pyrrolidin-2-one / 1 h / 0 °C
2: lithium hydroxide; water / methanol; water / 1 h
3: N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane / 0.17 h / 20 °C
With
lithium hydroxide; water; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
iron(III)-acetylacetonate;
In
1-methyl-pyrrolidin-2-one; methanol; dichloromethane; water;