7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane

Base Information

• Chemical Name: 7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane
• CAS No.: 94195-16-1
• Molecular Formula: C₂₄H₃₄N₂O₃
• Molecular Weight: 398.546
• Mol file: 94195-16-1.mol

Synonyms:7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane

Chemical Property of 7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane

There total 12 articles about 7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1,14-dihydroxy-3,12-dibenzyl-3,12-diaza-6,9-dioxatetradecane (113585-52-7) → 7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane (94195-16-1)

Guidance literature:

With p-toluenesulfonyl chloride; tert-butyl alcohol; In 1,4-dioxane; for 12h; Heating;

DOI:10.1021/jo00243a041

Reference yield: 72.0%

1,2-bis-(2-iodoethoxy)ethane (36839-55-1) + 1,7-dibenzyl-4-oxa-1,7-diazaheptane (66582-25-0) → 7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane (94195-16-1)

Guidance literature:

With sodium carbonate; sodium iodide; In acetonitrile; for 19h; Heating;

DOI:10.1016/S0040-4039(00)84009-5 DOI:10.1021/jo00376a059

Reference yield: 65.0%

benzyl chloride (100-44-7) + Kryptofix 21 (31249-95-3) → 7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane (94195-16-1)

Guidance literature:

With sodium hydroxide; In chloroform; water; Ambient temperature;

DOI:10.1246/bcsj.57.2685

upstream raw materials:

1,2-bis-(2-iodoethoxy)ethane

1,7-dibenzyl-4-oxa-1,7-diazaheptane

1,14-dihydroxy-3,12-dibenzyl-3,12-diaza-6,9-dioxatetradecane

benzyl chloride

Downstream raw materials:

N,N'-bis(2-nitrobenzyl)-4,10-diaza-15-crown-5

Kryptofix 21

Refernces

• 1、 Bradshaw, Jerald S.,Krakowiak, Krzysztof E.,Bruening, Ronald L.,Tarbet, Bryon J.,Savage, Paul B.,Izatt, Reed M.. "Synthesis of (Allyloxy)methyl-Substituted Diaza-18-crown-6 Compounds for Attachment to Silica Gel". . p. 3190 - 3195. Retrieved 2007/10/02.
• 2、 Gatto, Vincent J.,Arnold, Kristin A.,Viscariello, Anthony M.,Miller, Steven R.,Morgan, Charles R.,Gokel, George W.. "Syntheses and Binding Properties of Bibracchial Lariat Ethers (BIBLEs): Survey of Synthetic Methods and Cation Selectivities". . p. 5373 - 5384. Retrieved 2007/10/02.