4-Benzoylbiphenyl

Base Information

• Chemical Name: 4-Benzoylbiphenyl
• CAS No.: 2128-93-0
• Molecular Formula: C19H14O
• Molecular Weight: 258.32
• Hs Code.: 29143990
• European Community (EC) Number: 218-345-2
• NSC Number: 97365,55283
• UNII: UK25C63WBD
• DSSTox Substance ID: DTXSID4062193
• Nikkaji Number: J149.803G
• Wikidata: Q72440222
• Mol file: 2128-93-0.mol

Synonyms:4-Benzoylbiphenyl;2128-93-0;4-Phenylbenzophenone;phenyl-(4-phenylphenyl)methanone;p-Phenylbenzophenone;Benzophenone, 4-phenyl-;p-Benzoylbiphenyl;Methanone, [1,1'-biphenyl]-4-ylphenyl-;4-Diphenyl phenyl ketone;p-Biphenylyl phenyl ketone;Trigonal 12;4-Biphenylyl phenyl ketone;4-phenyl benzophenone;Eusolex 3490;Phenyl p-biphenylyl ketone;4-Benzoyldiphenyl;[1,1'-Biphenyl]-4-yl(phenyl)methanone;4-Diphenylphenyl ketone;MFCD00003079;NSC 55283;NSC 97365;(1,1'-Biphenyl)-4-yl phenylmethanone;UK25C63WBD;Methanone, (1,1'-biphenyl)-4-ylphenyl-;(Biphenyl-4-yl)(phenyl)methanone;EINECS 218-345-2;NSC-55283;NSC-97365;BRN 1876092;AI3-11253;Methanone, (1,1'-biphenyl)-4-yl phenyl-;Methanone,1'-biphenyl]-4-ylphenyl-;((1,1'-biphenyl)-4-yl)phenylmethanone;Maybridge4_000539;4-Benzoylbiphenyl, 99%;4-(Phenylcarbonyl)biphenyl;UNII-UK25C63WBD;NCIOpen2_001988;SCHEMBL41657;biphenyl-4-yl(phenyl)methanone;biphenyl-4-yl-phenyl-methanone;DTXSID4062193;LYXOWKPVTCPORE-UHFFFAOYSA-;(Biphenyl-4-yl)(phenyl)methanon;HMS1522I11;NSC55283;NSC97365;CCG-46778;(1,1'-biphenyl)-4-ylphenylmethanone;AKOS000277063;AM84742;CS-W012536;PS-7380;IDI1_031121;NCGC00177471-01;AC-13762;LS-91132;SY005697;[1,1'-Biphenyl]-4-yl(phenyl)methanone #;{[1,1'-biphenyl]-4-yl}(phenyl)methanone;Benzophenone, 4-phenyl- (6CI,7CI,8CI);FT-0619397;P1116;4-07-00-01824 (Beilstein Handbook Reference);SR-01000636452-1;W-107563;BRD-K38568968-001-01-5

Chemical Property of 4-Benzoylbiphenyl

Chemical Property:

• Appearance/Colour: off white crystalline powder
• Vapor Pressure: 3.11E-07mmHg at 25°C
• Melting Point: 99-101 °C
• Refractive Index: 1.609
• Boiling Point: 419.1 °C at 760 mmHg
• Flash Point: 190.7 °C
• PSA: 17.07000
• Density: 1.266 g/cm³
• LogP: 4.58460
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), Methanol (Slightly, Heated)
• Water Solubility.: 73.6μg/L at 20℃
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 258.104465066
• Heavy Atom Count: 20
• Complexity: 302

Purity/Quality:

99%, ^*data from raw suppliers

4-Benzoylbiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,Xn
• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)C3=CC=CC=C3
• Uses: 4-Benzoylbiphenyl is a reagent used in the synthesis of multicolored mechanochromic luminogen molecules.

Technology Process of 4-Benzoylbiphenyl

There total 155 articles about 4-Benzoylbiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C27H19N3O2 (82820-04-0) → 4-Phenylurazole (15988-11-1) + biphenyl-4-yl-phenyl-methanone (2128-93-0)

Guidance literature:

With water; for 1080h;

Reference yield: 69.0%

(4-bromophenyl)(phenyl)methanone (90-90-4) + triphenylbismuthane (603-33-8) → biphenyl (92-52-4,1594-86-1) + biphenyl-4-yl-phenyl-methanone (2128-93-0)

Guidance literature:

With caesium carbonate; triphenylphosphine; palladium dichloride; In N,N-dimethyl acetamide; at 90 ℃; for 2h;

DOI:10.1016/j.tet.2008.04.011

Reference yield: 64.0%

1,4-dibenzoylbenzene (3016-97-5) → biphenyl-4-yl-phenyl-methanone (2128-93-0) + [1,1';4',1'']terphenyl (92-94-4,94363-13-0)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; IMes^Me hydrochloride ; sodium t-butanolate; In toluene; at 160 ℃; for 18h; Glovebox; Inert atmosphere;

DOI:10.1021/jacs.6b12293

upstream raw materials:

diethyl ether

(2RS,3SR)-1-biphenyl-4-yl-2,3-epoxy-3-phenyl-propan-1-one

benzene

biphenyl

Downstream raw materials:

benzoic acid

biphenyl-4-carboxylic acid

Biphenyl-4-yl-phenyl-o-tolyl-methanol

4-(1-phenylvinyl)-1,1′-biphenyl

Refernces

• 1、 Paul, Dipankar,Rudra, Siddheswar,Rahman, Prabin,Khatua, Snehadrinarayan,Pradhan, Mukul,Chatterjee, Paresh Nath. "Synthesis and characterization of Pd-γ-Fe2O3 nanocomposite and its application as a magnetically recyclable catalyst in ligand-free Suzuki-Miyaura reaction in water". . p. 96 - 102. Retrieved 2018.
• 2、 Lim, Kyoung-Chan,Hong, Young-Taek,Kim, Sunggak. "Carboxylic phosphoric anhydrides as a new coupling partner in Pd-catalyzed coupling reactions: A new ketone synthesis". . p. 1851 - 1854. Retrieved 2006.
• 3、 Oswal, Preeti,Arora, Aayushi,Kaushal, Jolly,Rao, Gyandshwar Kumar,Kumar, Sushil,Singh, Ajai K.,Kumar, Arun. "Ultra-small palladium nano-particles synthesized using bulky S/Se and N donor ligands as a stabilizer: Application as catalysts for Suzuki-Miyaura coupling". . p. 22313 - 22319. Retrieved 2019.
• 4、 Tang, Zhen-Yu,Lu, Yong,Hu, Qiao-Sheng. "Direct synthesis of ferrocenylmethylphosphines from ferrocenylmethyl alcohols and their application as ligands for room temperature Pd(0)-catalyzed Suzuki cross-couplings of aryl bromides". . p. 297 - 300. Retrieved 2003.
• 5、 Ioannou, Polydoros-Chrysovalantis,Arbez-Gindre, Cécile,Zoumpanioti, Maria,Raptopoulou, Catherine P.,Psycharis, Vassilis,Kostas, Ioannis D.,Kyritsis, Panayotis. "Catalytic reactivity of the complexes [Pd{(Ph2P)2N(tBu)-P,P′}X2], X = Cl, Br, I, in the Suzuki-Miyaura C?C coupling reaction: Probing effects of the halogeno ligand X? and the ligand's tBu group". . p. 40 - 46. Retrieved 2019.
• 6、 Arora, Aayushi,Kaushal, Jolly,Kumar, Arun,Nautiyal, Divyanshu,Oswal, Preeti,Singh, Siddhant. "Suzuki?Miyaura coupling and O?arylation reactions catalysed by palladium(II) complexes of bulky ligands bearing naphthalene core, Schiff base functionality and biarylphosphine moiety". . . Retrieved 2022/01/19.
• 7、 Zhong, Jing,Zhou, Wuxin,Yan, Xufei,Xia, Ying,Xiang, Haifeng,Zhou, Xiangge. "Selective Activation of Unstrained C(O)-C Bond in Ketone Suzuki-Miyaura Coupling Reaction Enabled by Hydride-Transfer Strategy". . p. 1372 - 1377. Retrieved 2022/02/23.